Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVRL1 | P37023 | 11/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL59811 | 0.87 | ACVRL1 (0.48) | ACVRL1PIK3CDNTRK1NTRK2 | |
| SCHEMBL59980 | 0.85 | ACVRL1 (0.63) | ACVRL1PIK3CD | |
| SCHEMBL16021414 | 0.85 | ACVRL1 (0.50) | ACVRL1PIK3CDNTRK1NTRK2 | |
| SCHEMBL5076725 | 0.85 | ACVRL1 (0.49) | ACVRL1PIK3CDNTRK1NTRK2 | |
| SCHEMBL5136418 | 0.84 | ACVRL1 (0.64) | ACVRL1PIK3CD | |
| SCHEMBL59716 | 0.82 | ACVRL1 (0.52) | ACVRL1PIK3CD | |
| SCHEMBL16011258 | 0.82 | ACVRL1 (0.59) | ACVRL1PIK3CD | |
| SCHEMBL5077805 | 0.79 | ACVRL1 (0.44) | ACVRL1 | |
| SCHEMBL22677098 | 0.78 | ACVRL1 (0.48) | ACVRL1 | |
| SCHEMBL16021704 | 0.78 | ACVRL1 (0.45) | ACVRL1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957485-B1 | SUBSTITUTED 4-AMINO-PYRROLOTRIAZINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS | BAYER HEALTHCARE LLC (US) | 2013-02-13 | — | — | EP | disclosed |