Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 13/20 | 0.67 |
| ▸ | ACACA | Q13085 | 13/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14689499 | 1.00 | ACACB (0.67) | ACACBACACATHRBDAPK3NTRK1 | |
| SCHEMBL14689500 | 1.00 | ACACB (0.67) | ACACBACACATHRBDAPK3NTRK1 | |
| SCHEMBL2348559 | 0.91 | ACACB (0.81) | ACACBACACATHRBDAPK3NTRK1 | |
| SCHEMBL14689498 | 0.91 | ACACB (0.81) | ACACBACACATHRBDAPK3NTRK1 | |
| SCHEMBL14700718 | 0.91 | ACACB (0.81) | ACACBACACATHRBDAPK3NTRK1 | |
| SCHEMBL2353429 | 0.89 | ACACB (0.84) | ACACBACACADAPK3NTRK1PIM1 | |
| SCHEMBL14161224 | 0.89 | ACACB (0.84) | ACACBACACADAPK3NTRK1PIM1 | |
| SCHEMBL2352719 | 0.89 | ACACB (0.84) | ACACBACACADAPK3NTRK1PIM1 | |
| SCHEMBL14689966 | 0.89 | ACACB (0.84) | ACACBACACADAPK3NTRK1PIM1 | |
| SCHEMBL14700737 | 0.89 | ACACB (0.84) | ACACBACACADAPK3NTRK1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130040935-A1 | CYCLIC KETO-ENOLS FOR THERAPY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-02-14 | — | — | US | disclosed |
| US-20130040935-A1 | CYCLIC KETO-ENOLS FOR THERAPY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130040935-A1 | CYCLIC KETO-ENOLS FOR THERAPY | AKR1B1, AKR1C3, AKR1A1 | ACACB 310/4885ACACA 541/4885THRB 1069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.