SCHEMBL14701157

SCHEMBL14701157

CNC1C(=O)N(C)C(=O)N(C)C1=O

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.42
ALDH1A1 P00352 5/20 0.42
HSD17B10 Q99714 5/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
ADRA2C P18825 1/20 0.33
KDM4A O75164 1/20 0.33
KDM4C Q9H3R0 1/20 0.33
GAA P10253 3/20 0.32
THRB P10828 2/20 0.32
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8297572 0.89
SCHEMBL30958906 0.77 MAPT (0.45) MAPTALDH1A1HSD17B10MEN1KMT2A
SCHEMBL200674 0.69 MAPT (0.41) MAPTALDH1A1HSD17B10MEN1KMT2A
SCHEMBL11820394 0.67 MAPT (0.40) MAPTALDH1A1HSD17B10MEN1KMT2A
Calcium SCHEMBL30891545 0.67 MAPT (0.40) MAPTALDH1A1HSD17B10MEN1KMT2A
SCHEMBL8468520 0.67 MAPT (0.40) MAPTALDH1A1HSD17B10MEN1KMT2A
SCHEMBL1263023 0.67 MAPT (0.40) MAPTALDH1A1HSD17B10MEN1KMT2A
SCHEMBL1263355 0.67 MAPT (0.40) MAPTALDH1A1HSD17B10MEN1KMT2A
SCHEMBL22628805 0.67 MAPT (0.40) MAPTALDH1A1HSD17B10MEN1KMT2A
SCHEMBL4006398 0.67 MAPT (0.40) MAPTALDH1A1HSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8664289-B2 Dye and coloring photosensitive composition ADEKA CORPORATION (JP) 2014-03-04 US disclosed
US-8664289-B2 Dye and coloring photosensitive composition ADEKA CORPORATION (JP) 2014-03-04 US disclosed
EP-2620476-A1 PIGMENT AND COLORED PHOTOSENSITIVE COMPOSITION Adeka Corporation (JP) 2013-07-31 EP disclosed
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION ADEKA CORPORATION (JP) 2013-02-14 US disclosed
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION ADEKA CORPORATION (JP) 2013-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION IK, CRY1, ABCG2 MAPT 458/4885ALDH1A1 155/4885HSD17B10 833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.