Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22436892 | 0.95 | — | — | |
| SCHEMBL17685112 | 0.95 | — | — | |
| SCHEMBL20138869 | 0.84 | — | — | |
| SCHEMBL9667909 | 0.77 | THRB (0.39) | THRBLMNA | |
| SCHEMBL28483386 | 0.77 | THRB (0.39) | THRBLMNA | |
| SCHEMBL27201024 | 0.77 | THRB (0.39) | THRBLMNA | |
| SCHEMBL6236877 | 0.77 | THRB (0.39) | THRBLMNA | |
| SCHEMBL28552565 | 0.77 | THRB (0.39) | THRBLMNA | |
| SCHEMBL27201025 | 0.77 | THRB (0.39) | THRBLMNA | |
| SCHEMBL27201026 | 0.77 | THRB (0.39) | THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013022238-A2 | TRICYCLIC GLYCOSYLATED DERIVATIVE COMPOUND, A PRODUCTION METHOD THEREFOR, AND AN IMMUNOSUPPRESSANT PHARMACEUTICAL COMPOSITION COMPRISING A TACROLIMUS GLYCOSYLATION DERIVATIVE | (주)제노텍 (KR) | 2013-02-14 | — | — | WO | disclosed |