Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1470159 | 1.00 | ALDH1A1 (0.56) | ALDH1A1SOAT1TSHRTHRBABCB11 | |
| SCHEMBL1470377 | 1.00 | ALDH1A1 (0.56) | ALDH1A1SOAT1TSHRTHRBABCB11 | |
| SCHEMBL1469365 | 1.00 | ALDH1A1 (0.56) | ALDH1A1SOAT1TSHRTHRBABCB11 | |
| SCHEMBL1128471 | 0.93 | ALDH1A1 (0.65) | ALDH1A1SOAT1TSHRTHRBCYP3A4 | |
| SCHEMBL1469994 | 0.91 | ALDH1A1 (0.56) | ALDH1A1SOAT1TSHRTHRBABCB11 | |
| SCHEMBL1471201 | 0.91 | ALDH1A1 (0.56) | ALDH1A1SOAT1TSHRTHRBABCB11 | |
| SCHEMBL1471816 | 0.91 | ALDH1A1 (0.56) | ALDH1A1SOAT1TSHRTHRBABCB11 | |
| SCHEMBL1469514 | 0.91 | ALDH1A1 (0.56) | ALDH1A1SOAT1TSHRTHRBABCB11 | |
| SCHEMBL1469655 | 0.91 | ALDH1A1 (0.56) | ALDH1A1SOAT1TSHRTHRBABCB11 | |
| SCHEMBL1470111 | 0.91 | ALDH1A1 (0.56) | ALDH1A1SOAT1TSHRTHRBABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1431274-B1 | Synthesis of mono-N-substituted functionalized anilines | CONSORZIO INTERUNIVERSITARIO N (IT) | 2007-08-15 | — | — | EP | claimed |
| US-20040127747-A1 | Synthesis of mono-N-substituted functionalized anilines | CONSORZIO INTERUNIVERSITARIO NAZIONALE "LA CHIMICA PER L'AMBIENTE" | 2004-07-01 | — | — | US | claimed |
| EP-1431274-A1 | Synthesis of mono-N-substituted functionalized anilines | Consorzio Interuniversitario Nazionale "La Chimica Per L'Ambiente" (IT) | 2004-06-23 | — | — | EP | claimed |
| US-20170349587-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO., LTD. (JP) | 2017-12-07 | — | — | US | disclosed |
| EP-3249735-A2 | NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY USING THE SAME | Mitsubishi Chemical Corporation (JP) | 2017-11-29 | — | — | EP | disclosed |
| US-9758515-B2 | Substituted polycyclic carbamoyl pyridone derivative prodrug | SHIONOGI & CO., LTD. (JP) | 2017-09-12 | — | — | US | disclosed |
| US-9231274-B2 | Nonaqueous electrolyte solution and lithium secondary battery using same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2016-01-05 | — | — | US | disclosed |
| US-9136560-B2 | Nonaqueous electrolyte solution and lithium secondary battery using same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2015-09-15 | — | — | US | disclosed |
| US-20150111854-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO (JP) | 2015-04-23 | — | — | US | disclosed |
| US-8987441-B2 | Substituted polycyclic carbamoyl pyridone derivative prodrug | SHIONOGI & CO., LTD. (JP) | 2015-03-24 | — | — | US | disclosed |
| US-20130196225-A1 | NONAQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY USING SAME | MITSUBISHI CHEMICAL CORPORATION (JP) | 2013-08-01 | — | — | US | disclosed |
| US-20120244426-A1 | NONAQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY USING SAME | MITSUBISHI CHEMICAL CORPORATION (JP) | 2012-09-27 | — | — | US | disclosed |
| US-8043745-B2 | Non-aqueous electrolyte solution and lithium secondary battery using same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2011-10-25 | — | — | US | disclosed |
| US-8007938-B2 | Nonaqueous electrolyte solution and lithium secondary battery using same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2011-08-30 | — | — | US | disclosed |
| US-20110070485-A1 | NONAQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY USING SAME | MITSUBISHI CHEMICAL CORPORATION (JP) | 2011-03-24 | — | — | US | disclosed |
| US-20070224514-A1 | Nonaqueous Electrolyte Solution and Lithium Secondary Battery Using Same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-09-27 | — | — | US | disclosed |
| EP-1431274-B1 | Synthesis of mono-N-substituted functionalized anilines | CONSORZIO INTERUNIVERSITARIO N (IT) | 2007-08-15 | — | — | EP | disclosed |
| EP-1744394-A1 | NONAQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY USING SAME | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-01-17 | — | — | EP | disclosed |
| US-20040127747-A1 | Synthesis of mono-N-substituted functionalized anilines | CONSORZIO INTERUNIVERSITARIO NAZIONALE "LA CHIMICA PER L'AMBIENTE" | 2004-07-01 | — | — | US | disclosed |
| EP-1431274-A1 | Synthesis of mono-N-substituted functionalized anilines | Consorzio Interuniversitario Nazionale "La Chimica Per L'Ambiente" (IT) | 2004-06-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150111854-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | PREP, UNG, DPP4 | ALDH1A1 1564/4885SOAT1 4661/4885TSHR 3454/4885 |
| US-20040127747-A1 | Synthesis of mono-N-substituted functionalized anilines | AS3MT, DNMT3L, DNMT3A | ALDH1A1 2778/4885SOAT1 1351/4885TSHR 4753/4885 |
| US-20170349587-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | PREP, UNG, DPP4 | ALDH1A1 1564/4885SOAT1 4661/4885TSHR 3454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.