SCHEMBL14701597

SCHEMBL14701597

CC1(C)c2ccccc2-c2ccc(-c3ccc4c(=O)c5cc(-c6ccc7c(c6)C(C)(C)c6ccccc6-7)ccc5oc4c3)cc21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 3/20 0.45
SENP7 Q9BQF6 3/20 0.45
SENP6 Q9GZR1 3/20 0.45
HCRTR1 O43613 2/20 0.45
NPC1 O15118 8/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
RAB9A P51151 7/20 0.40
MAOA P21397 5/20 0.40
ATM Q13315 1/20 0.39
MAPT P10636 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.38
GLA P06280 1/20 0.38
CYP3A4 P08684 1/20 0.38
PGAM1 P18669 1/20 0.38
CASP1 P29466 1/20 0.38
CASP7 P55210 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12181813 0.95 HCRTR1 (0.46) CASP3SENP7SENP6HCRTR1NPC1
SCHEMBL12181754 0.95 CASP3 (0.46) CASP3SENP7SENP6HCRTR1NPC1
SCHEMBL26503459 0.94 CASP3 (0.52) CASP3SENP7SENP6HCRTR1NPC1
SCHEMBL10055192 0.94 CASP3 (0.52) CASP3SENP7SENP6HCRTR1NPC1
SCHEMBL26936244 0.92 CASP3 (0.40) CASP3SENP7SENP6HCRTR1NPC1
SCHEMBL12181762 0.91 CASP3 (0.43) CASP3SENP7SENP6NPC1MEN1
SCHEMBL12181801 0.90 CASP3 (0.49) CASP3SENP7SENP6HCRTR1NPC1
SCHEMBL12181791 0.90 CASP3 (0.49) CASP3SENP7SENP6HCRTR1NPC1
SCHEMBL26503458 0.89 CASP3 (0.54) CASP3SENP7SENP6HCRTR1NPC1
SCHEMBL26936264 0.88 HCRTR1 (0.40) CASP3SENP7SENP6HCRTR1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9269911-B2 Organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2016-02-23 US disclosed
US-9269911-B2 Organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2016-02-23 US disclosed
US-20130037791-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2013-02-14 US disclosed
US-20130037791-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2013-02-14 US disclosed