SCHEMBL14701623

SCHEMBL14701623

c1ccc(-c2c(-c3ccc(-n4c5ccccc5c5ccccc54)cc3)c(-c3ccccc3)c(-c3ccccc3)c(-n3c4ccccc4c4ccccc43)c2-c2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.59
KDM4E B2RXH2 2/20 0.59
ATM Q13315 1/20 0.59
KMT2A Q03164 3/20 0.47
HDAC4 P56524 1/20 0.43
IL1R1 P14778 1/20 0.41
ALDH1A1 P00352 2/20 0.40
MEN1 O00255 1/20 0.40
MAPT P10636 1/20 0.40
HTT P42858 1/20 0.40
PTPN1 P18031 2/20 0.38
ESR1 P03372 4/20 0.35
ESR2 Q92731 4/20 0.35
LMNA P02545 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
EDNRB P24530 1/20 0.35
EDNRA P25101 1/20 0.35
MAPK8 P45983 2/20 0.34
RCE1 Q9Y256 1/20 0.34
MAPK9 P45984 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12345498 0.93 L3MBTL1 (0.68) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL65355 0.93 L3MBTL1 (0.68) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL64830 0.93 L3MBTL1 (0.68) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL29416722 0.93 L3MBTL1 (0.68) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL13286813 0.91 L3MBTL1 (0.65) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL3326442 0.91 KDM4E (0.52) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL13777104 0.89 L3MBTL1 (0.63) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL13777103 0.89 L3MBTL1 (0.63) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL10029967 0.89 KDM4E (0.50) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL36248 0.87 L3MBTL1 (0.65) L3MBTL1KDM4EATMKMT2AHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130037791-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2013-02-14 US disclosed
US-20130037791-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2013-02-14 US disclosed