SCHEMBL14701626

SCHEMBL14701626

CC1(C)OB(c2cccc(-c3cccc(-c4ccc5c(c4)-c4ccccc4C54c5ccccc5-c5ccccc54)c3)c2)OC1(C)C

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 10/20 0.48
LPL P06858 9/20 0.48
PDGFRB P09619 1/20 0.33
KDR P35968 1/20 0.33
PDK2 Q15119 3/20 0.33
PRMT5 O14744 1/20 0.32
WDR77 Q9BQA1 1/20 0.32
EGFR P00533 1/20 0.31
DGAT1 O75907 1/20 0.31
IRAK4 Q9NWZ3 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24741552 0.92 LIPG (0.48) LIPGLPLPDK2DGAT1
SCHEMBL10042927 0.92 LIPG (0.48) LIPGLPLPDGFRBKDRPDK2
SCHEMBL5019888 0.92 LIPG (0.48) LIPGLPLPDK2DGAT1
SCHEMBL18864288 0.91 LIPG (0.49) LIPGLPLPDK2
SCHEMBL31708323 0.91 LIPG (0.49) LIPGLPLPDK2
SCHEMBL31050381 0.91 LIPG (0.49) LIPGLPLPDGFRBKDRPDK2
SCHEMBL806932 0.91 LIPG (0.49) LIPGLPLPDGFRBKDRPDK2
SCHEMBL24626384 0.88 LIPG (0.59) LIPGLPLPDGFRBKDRDGAT1
SCHEMBL24654450 0.87 LIPG (0.46) LIPGLPLPDK2DGAT1
SCHEMBL30951715 0.87 LIPG (0.43) LIPGLPLPDGFRBKDRPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9269911-B2 Organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2016-02-23 US disclosed
US-9269911-B2 Organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2016-02-23 US disclosed
US-20130037791-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2013-02-14 US disclosed
US-20130037791-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2013-02-14 US disclosed