Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 5/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.38 |
| ▸ | CPB1 | P15086 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.32 |
| ▸ | HCAR1 | Q9BXC0 | 4/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3273845 | 0.98 | CPB2 (0.40) | CDK5CDK5R1CPB2CPB1GSK3B | |
| SCHEMBL15236765 | 0.98 | CPB2 (0.40) | CDK5CDK5R1CPB2CPB1GSK3B | |
| SCHEMBL14631017 | 0.84 | CPB2 (0.42) | CDK5CDK5R1CPB2ALDH1A1KDM2B | |
| SCHEMBL12333257 | 0.84 | CPB2 (0.43) | CDK5CDK5R1CPB2GSK3BWDR5 | |
| SCHEMBL14631015 | 0.84 | CPB2 (0.42) | CDK5CDK5R1CPB2ALDH1A1KDM2B | |
| SCHEMBL14631062 | 0.84 | CPB2 (0.43) | CDK5CDK5R1CPB2GSK3BWDR5 | |
| SCHEMBL14631484 | 0.84 | CPB2 (0.42) | CDK5CDK5R1CPB2ALDH1A1KDM2B | |
| SCHEMBL14653682 | 0.83 | CDK5 (0.34) | CDK5CDK5R1CPB2GSK3BWDR5 | |
| SCHEMBL14631438 | 0.82 | CPB2 (0.47) | CDK5CDK5R1CPB2CPB1GSK3B | |
| SCHEMBL14631151 | 0.80 | CPB2 (0.40) | CDK5CDK5R1CPB2KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9284350-B2 | IAP BIR domain binding compounds | PHARMASCIENCE INC. (CA) | 2016-03-15 | — | — | US | disclosed |
| US-20130040892-A1 | IAP BIR DOMAIN BINDING COMPOUNDS | PHARMASCIENCE INC. (CA) | 2013-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130040892-A1 | IAP BIR DOMAIN BINDING COMPOUNDS | BIRC5, BIRC2, BIRC3 | CDK5 2613/4885CDK5R1 1924/4885CPB2 3960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.