SCHEMBL14701715

SCHEMBL14701715

CCC(C)(C)Oc1ccc(Cc2ccc(OC(=O)C(C)(C)CC)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ELANE P08246 11/20 0.59
OPRK1 P41145 1/20 0.48
PPARA Q07869 4/20 0.39
PPARG P37231 1/20 0.39
ABCB11 O95342 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
HTR2A P28223 1/20 0.36
PMP22 Q01453 1/20 0.36
KMT2A Q03164 2/20 0.36
PLA2G1B P04054 1/20 0.36
ATG4B Q9Y4P1 1/20 0.36
THRB P10828 1/20 0.35
SAE1 Q9UBE0 1/20 0.35
UBA2 Q9UBT2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12021518 0.92 ELANE (0.51) ELANEOPRK1PPARAPPARGABCB11
SCHEMBL14679473 0.88 ELANE (0.59) ELANEOPRK1PPARAPPARGABCB11
SCHEMBL21030113 0.88 ELANE (0.54) ELANEOPRK1PPARAPPARGABCB11
SCHEMBL12085813 0.88 ELANE (0.48) ELANEOPRK1PPARAPPARGABCB11
SCHEMBL807094 0.85 ELANE (0.46) ELANEPPARAABCB11CYP1A2CYP3A4
SCHEMBL12907932 0.84 ELANE (0.44) ELANEOPRK1PPARAABCB11CYP1A2
SCHEMBL12907935 0.83 ELANE (0.44) ELANEOPRK1PPARAABCB11CYP1A2
SCHEMBL13063798 0.81 ELANE (0.50) ELANEOPRK1PPARAPPARGABCB11
SCHEMBL683395 0.81 ELANE (0.53) ELANEOPRK1PPARAPPARGABCB11
SCHEMBL12737001 0.81 ELANE (0.56) ELANEKMT2APLA2G1BATG4BTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130040234-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, MANUFACTURING METHOD THEREFOR AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2013-02-14 US disclosed