SCHEMBL14701778

SCHEMBL14701778

CCC(C)(C)Oc1ccc(C2(c3ccc(OC(=O)C(C)(C)C)c(C)c3)c3ccccc3-c3ccccc32)cc1C

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
LMNA P02545 2/20 0.36
MAPT P10636 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ELANE P08246 14/20 0.35
VDR P11473 1/20 0.33
ALDH1A1 P00352 2/20 0.32
CYP3A4 P08684 1/20 0.32
HIF1A Q16665 1/20 0.32
ADRB2 P07550 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18648958 0.90 ESR1 (0.45) ESR1ESR2LMNAMAPTNPSR1
SCHEMBL18648920 0.90 ESR1 (0.41) ESR1ESR2ELANE
SCHEMBL12346214 0.90 ESR1 (0.41) ESR1ESR2LMNAMAPTNPSR1
SCHEMBL10065614 0.88 ESR1 (0.40) ESR1ESR2ELANE
SCHEMBL14192279 0.88 ESR1 (0.43) ESR1ESR2NPSR1ELANEVDR
SCHEMBL823264 0.85 ESR1 (0.42) ESR1ESR2ELANEALDH1A1
SCHEMBL13448621 0.83 ESR1 (0.40) ESR1ESR2ELANE
SCHEMBL10065615 0.82 ESR1 (0.40) ESR1ESR2ELANE
SCHEMBL19750309 0.82 ESR1 (0.43) ESR1ESR2LMNAMAPTNPSR1
SCHEMBL10066097 0.80 ESR1 (0.41) ESR1ESR2NPSR1ALDH1A1ADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8455611-B2 Optical film TEIJIN CHEMICALS LTD. (JP) 2013-06-04 US disclosed
US-20130040234-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, MANUFACTURING METHOD THEREFOR AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2013-02-14 US disclosed