Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28774334 | 0.81 | CYP1A2 (0.58) | CYP1A2CYP2A6TAAR1IDO1KCNH2 | |
| SCHEMBL13799439 | 0.80 | IDO1 (0.48) | TAAR1AGXTIDO1KCNH2ALDH1A1 | |
| SCHEMBL13870180 | 0.77 | CYP2C19 (0.61) | CYP1A2TDP1L3MBTL1CYP2D6CYP2C19 | |
| SCHEMBL12337765 | 0.76 | IDO1 (0.48) | CYP1A2CYP2A6TAAR1IDO1TDP1 | |
| SCHEMBL14346666 | 0.76 | CYP1A2 (0.52) | CYP1A2CYP2A6TAAR1AGXTIDO1 | |
| SCHEMBL1709949 | 0.76 | CYP1A2 (0.60) | CYP1A2CYP2D6CYP2C19MEN1ALDH1A1 | |
| SCHEMBL11579733 | 0.75 | ALDH1A1 (0.42) | CYP1A2TDP1CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL11086271 | 0.74 | CYP1A2 (0.50) | CYP1A2CYP2A6TAAR1AGXTIDO1 | |
| SCHEMBL21628358 | 0.74 | CYP1A2 (0.56) | CYP1A2CYP2A6TAAR1AGXTIDO1 | |
| SCHEMBL10736820 | 0.74 | CYP1A2 (0.50) | CYP1A2CYP2A6TAAR1AGXTIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130041000-A1 | NOVEL AZOLE COMPOUND | AJINOMOTO CO., INC. (JP) | 2013-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130041000-A1 | NOVEL AZOLE COMPOUND | LPAR1, LPAR2, LPAR3 | CYP1A2 549/4885CYP2A6 1144/4885TAAR1 579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.