Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 6/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 6/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 6/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14705297 | 0.82 | NOTUM (0.55) | SMN1; SMN2CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL811848 | 0.78 | POLB (0.51) | POLBGAAESR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL9230128 | 0.78 | POLB (0.51) | POLBGAAESR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL15222054 | 0.78 | POLB (0.51) | POLBGAAESR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL29659945 | 0.78 | POLB (0.51) | POLBGAAESR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL23346885 | 0.77 | PLAU (0.42) | GAASMN1; SMN2CHRM2CHRM1TSHR | |
| SCHEMBL9396982 | 0.77 | GAA (0.50) | POLBGAAESR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL28846544 | 0.77 | POLB (0.47) | POLBGAAESR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL6114443 | 0.77 | POLB (0.47) | POLBGAAESR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL24176565 | 0.74 | ESR1 (0.44) | POLBGAAESR1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013021044-A1 | 1,2,4-TRIAZOLYL-SUBSTITUTED KETO-ENOLS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-02-14 | — | — | WO | disclosed |