Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 5/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 5/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 5/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9230128 | 1.00 | POLB (0.51) | POLBL3MBTL1ESR1GAASMN1; SMN2 | |
| SCHEMBL15222054 | 1.00 | POLB (0.51) | POLBL3MBTL1ESR1GAASMN1; SMN2 | |
| SCHEMBL811848 | 1.00 | POLB (0.51) | POLBL3MBTL1ESR1GAASMN1; SMN2 | |
| Citric Acid SCHEMBL10413701 | 0.80 | CHRM2 (0.45) | POLBL3MBTL1ESR1GAASMN1; SMN2 | |
| SCHEMBL7733992 | 0.79 | NOTUM (0.55) | SMN1; SMN2CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL811795 | 0.79 | NOTUM (0.55) | SMN1; SMN2CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL31672940 | 0.79 | NOTUM (0.55) | SMN1; SMN2CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL6890897 | 0.79 | NOTUM (0.55) | SMN1; SMN2CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL6114443 | 0.78 | POLB (0.47) | POLBL3MBTL1ESR1GAASMN1; SMN2 | |
| SCHEMBL14705669 | 0.78 | POLB (0.47) | POLBL3MBTL1ESR1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4635565-A1 | PRENYLATED TETRAHYDROQUINOLINES AND QUINOLINES WITH PPAR AGONIST ACTIVITY | Fundación para la Investigación del Hospital Clínico de la Comunidad Valenciana (INCLIVA) (ES) | 2025-10-22 | — | — | EP | disclosed |
| CN-116239529-B | Preparation method of N-methyltetrahydroquinoline alkaloid with participation of carbon dioxide | 山西大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-116239529-A | Preparation method of N-methyltetrahydroquinoline alkaloid with participation of carbon dioxide | 山西大学 | 2023-06-09 | — | — | CN | disclosed |
| CN-111094267-B | Sulfonyl-substituted bicyclic compounds as ROR gamma inhibitors | 正大天晴药业集团股份有限公司 | 2022-06-14 | — | — | CN | disclosed |