Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | FPR2 | P25090 | 2/20 | 0.42 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HRH1 | P35367 | 6/20 | 0.38 |
| ▸ | CCR3 | P51677 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | SGK1 | O00141 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1470616 | 0.98 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 | |
| SCHEMBL1470859 | 0.87 | SLC6A4 (0.39) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 | |
| SCHEMBL1473038 | 0.87 | FPR2 (0.45) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 | |
| Hydrochloric Acid SCHEMBL1471241 | 0.85 | FPR2 (0.44) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 | |
| Hydrochloric Acid SCHEMBL1470564 | 0.85 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 | |
| SCHEMBL1471275 | 0.83 | AR (0.38) | SLC6A2SLC6A4SLC6A3CSF1RPDGFRB | |
| Hydrochloric Acid SCHEMBL1470312 | 0.82 | AR (0.38) | SLC6A2SLC6A4SLC6A3CSF1RPDGFRB | |
| SCHEMBL1470774 | 0.79 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 | |
| SCHEMBL20982741 | 0.79 | NR4A1 (0.41) | ALDH1A1CSF1RPDGFRBKITPDGFRA | |
| SCHEMBL1471285 | 0.79 | SLC6A4 (0.44) | SLC6A2SLC6A4SLC6A3FPR2PROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215820-A1 | NOVEL ALKYL SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | ANIONA APS (DK) | 2009-08-27 | — | — | US | claimed |
| US-7547788-B2 | Alkyl substituted piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors | NEUROSEARCH A/S (DK) | 2009-06-16 | — | — | US | claimed |
| US-20070167487-A1 | Novel alkyl substituted piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors | ANIONA APS (DK) | 2007-07-19 | — | — | US | claimed |
| EP-1761493-A2 | ALKYL SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2007-03-14 | — | — | EP | claimed |
| WO-2005123679-A2 | ALKYL SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2005-12-29 | — | — | WO | claimed |
| US-20110086880-A1 | NOVEL ALKYL SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | PETERS DAN | 2011-04-14 | — | — | US | disclosed |
| US-7915419-B2 | Alkyl substituted piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors | NEUROSEARCH A/S (DK) | 2011-03-29 | — | — | US | disclosed |
| US-20090215820-A1 | NOVEL ALKYL SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | ANIONA APS (DK) | 2009-08-27 | — | — | US | disclosed |
| US-7547788-B2 | Alkyl substituted piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors | NEUROSEARCH A/S (DK) | 2009-06-16 | — | — | US | disclosed |
| US-20070167487-A1 | Novel alkyl substituted piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors | ANIONA APS (DK) | 2007-07-19 | — | — | US | disclosed |
| EP-1761493-A2 | ALKYL SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2007-03-14 | — | — | EP | disclosed |
| WO-2005123679-A2 | ALKYL SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2005-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215820-A1 | NOVEL ALKYL SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | SLC18A2, SLC6A2, SLC18A3 | SLC6A2 2/4885SLC6A4 4/4885SLC6A3 5/4885 |
| US-20070167487-A1 | Novel alkyl substituted piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors | SLC18A2, SLC6A2, SLC18A3 | SLC6A2 2/4885SLC6A4 4/4885SLC6A3 5/4885 |
| US-20110086880-A1 | NOVEL ALKYL SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | SLC18A2, SLC6A2, SLC18A3 | SLC6A2 2/4885SLC6A4 4/4885SLC6A3 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.