Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.38 |
| ▸ | BCDIN3D | Q7Z5W3 | 2/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4702287 | 1.00 | IDO1 (0.46) | IDO1TDO2GBA1HTR2ATAAR1 | |
| Hydrochloric Acid SCHEMBL28716274 | 0.98 | IDO1 (0.49) | IDO1TDO2GBA1HTR2ATAAR1 | |
| Hydrochloric Acid SCHEMBL29487201 | 0.98 | IDO1 (0.49) | IDO1TDO2GBA1HTR2ATAAR1 | |
| SCHEMBL30689582 | 0.86 | TAAR1 (0.47) | IDO1TDO2GBA1HTR2ATAAR1 | |
| SCHEMBL3542231 | 0.84 | TAAR1 (0.46) | HTR2ATAAR1ANPEPENPEP | |
| SCHEMBL25370972 | 0.82 | GBA1 (0.47) | IDO1TDO2GBA1TAAR1MAOA | |
| SCHEMBL8515046 | 0.82 | GBA1 (0.47) | IDO1TDO2GBA1TAAR1MAOA | |
| SCHEMBL1459476 | 0.82 | GBA1 (0.47) | IDO1TDO2GBA1TAAR1MAOA | |
| SCHEMBL12479861 | 0.82 | GBA1 (0.47) | IDO1TDO2GBA1TAAR1MAOA | |
| SCHEMBL16396890 | 0.82 | GBA1 (0.47) | IDO1TDO2GBA1TAAR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9196844-B2 | Method of synthesizing pyrazine derivative, and light-emitting element, light-emitting device, electronic device, and lighting device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2015-11-24 | — | — | US | disclosed |
| US-9196844-B2 | Method of synthesizing pyrazine derivative, and light-emitting element, light-emitting device, electronic device, and lighting device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2015-11-24 | — | — | US | disclosed |
| US-9196844-B2 | Method of synthesizing pyrazine derivative, and light-emitting element, light-emitting device, electronic device, and lighting device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2015-11-24 | — | — | US | disclosed |
| US-9159934-B2 | Organic material, light-emitting element, light-emitting device, electronic appliance, and lighting device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2015-10-13 | — | — | US | disclosed |
| US-9159934-B2 | Organic material, light-emitting element, light-emitting device, electronic appliance, and lighting device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2015-10-13 | — | — | US | disclosed |
| US-9159934-B2 | Organic material, light-emitting element, light-emitting device, electronic appliance, and lighting device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2015-10-13 | — | — | US | disclosed |
| US-20130323869-A1 | Organic Material, Light-Emitting Element, Light-Emitting Device, Electronic Appliance, and Lighting Device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2013-12-05 | — | — | US | disclosed |
| US-20130324729-A1 | Method of Synthesizing Pyrazine Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device | SEMICONDUCTOR ENERGY LABORATORY CO. LTD. (JP) | 2013-12-05 | — | — | US | disclosed |
| US-7915420-B2 | Aryl piperidine amides | JANSSEN PHARMACEUTICA NV (BE) | 2011-03-29 | — | — | US | disclosed |
| US-20080009521-A1 | Aryl Piperidine Amides | HUANG CHARLES Q | 2008-01-10 | — | — | US | disclosed |
| US-7276610-B2 | Aryl piperidine amides | JANSSEN PHARACEUTICA, NV (BE) | 2007-10-02 | — | — | US | disclosed |
| EP-1660472-A1 | ARYL PIPERIDINE AMIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005021525-A1 | ARYL PIPERIDINE AMIDES | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-03-10 | — | — | WO | disclosed |
| US-20050049239-A1 | Aryl piperidine amides | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-03-03 | — | — | US | disclosed |
| US-4129661-A | 4,5-Dihydro-2-lower alkoxycarbonylamino-4-phenylimidazoles and substituted phenyl derivatives thereof | SYNTEX (U.S.A.) INC. (US) | 1978-12-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009521-A1 | Aryl Piperidine Amides | BDNF, NTRK2, OPRL1 | IDO1 1235/4885TDO2 2985/4885GBA1 690/4885 |
| US-20050049239-A1 | Aryl piperidine amides | BDNF, NTRK2, OPRL1 | IDO1 1235/4885TDO2 2985/4885GBA1 690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.