Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | PKM | P14618 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14261920 | 0.86 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2PKMALDH1A1 | |
| SCHEMBL14261914 | 0.83 | RAB9A (0.55) | NPC1RAB9ASMN1; SMN2PKMALDH1A1 | |
| SCHEMBL14261925 | 0.80 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2PKMMAPT | |
| SCHEMBL14261917 | 0.77 | RAB9A (0.56) | NPC1RAB9ASMN1; SMN2PKMALDH1A1 | |
| SCHEMBL14262022 | 0.72 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2PKMALDH1A1 | |
| SCHEMBL14261921 | 0.69 | CTSA (0.55) | ALDH1A1HTT | |
| SCHEMBL653271 | 0.69 | CTNNB1 (1.00) | NPC1RAB9ASMN1; SMN2PKMALDH1A1 | |
| SCHEMBL14261915 | 0.67 | RAB9A (0.47) | RAB9ASMN1; SMN2ALDH1A1HTTPDE2A | |
| SCHEMBL11617713 | 0.67 | CTNNB1 (0.67) | NPC1RAB9ASMN1; SMN2PKMALDH1A1 | |
| SCHEMBL654355 | 0.66 | CTNNB1 (1.00) | PKMCTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1529042-B1 | ARYLAMIDES | INTERMED DISCOVERY GMBH (DE) | 2013-02-20 | — | — | EP | disclosed |