SCHEMBL14709013

SCHEMBL14709013

CC1(C)OC2[C@@H](O1)[C@H](NC(=O)OCc1ccccc1)C[C@@H]2O

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CPB1 P15086 2/20 0.50
ALDH1A1 P00352 3/20 0.45
GAA P10253 1/20 0.45
TSHR P16473 3/20 0.44
KDM1A O60341 1/20 0.41
MAOB P27338 1/20 0.41
EPHX1 P07099 1/20 0.41
NAAA Q02083 1/20 0.41
CYP3A4 P08684 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
CASP1 P29466 1/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2D6 P10635 2/20 0.40
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
CTSL P07711 1/20 0.40
CTSB P07858 1/20 0.40
CTSK P43235 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18560233 1.00 CPB1 (0.50) CPB1ALDH1A1GAATSHRKDM1A
SCHEMBL10249662 1.00 CPB1 (0.50) CPB1ALDH1A1GAATSHRKDM1A
SCHEMBL13974660 1.00 CPB1 (0.50) CPB1ALDH1A1GAATSHRKDM1A
SCHEMBL12321138 1.00 CPB1 (0.50) CPB1ALDH1A1GAATSHRKDM1A
SCHEMBL16378881 1.00 CPB1 (0.50) CPB1ALDH1A1GAATSHRKDM1A
SCHEMBL14709135 1.00 CPB1 (0.50) CPB1ALDH1A1GAATSHRKDM1A
SCHEMBL16800333 0.89 CPB1 (0.47) CPB1ALDH1A1GAATSHRKDM1A
SCHEMBL9274943 0.87 CPB1 (0.52) CPB1ALDH1A1GAATSHRKDM1A
SCHEMBL9886997 0.86 CPB1 (0.48) CPB1ALDH1A1GAATSHRKDM1A
SCHEMBL12036754 0.86 CPB1 (0.48) CPB1ALDH1A1GAATSHRKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013023511-A1 TRIAZOLOPYRIMIDINE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF 上海恒瑞医药有限公司 (CN) 2013-02-21 WO disclosed