Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 16/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | FPR3 | P25089 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | GPR183 | P32249 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | P2RY13 | Q9BPV8 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29688120 | 0.88 | P2RY12 (0.43) | P2RY12PGRADORA3CHRM1DRD1 | |
| SCHEMBL14709081 | 0.88 | P2RY12 (0.43) | P2RY12PGRADORA3CHRM1DRD1 | |
| SCHEMBL1509192 | 0.88 | P2RY12 (0.43) | P2RY12PGRADORA3CHRM1DRD1 | |
| SCHEMBL17679487 | 0.88 | P2RY12 (0.43) | P2RY12PGRADORA3CHRM1DRD1 | |
| SCHEMBL15859659 | 0.88 | P2RY12 (0.43) | P2RY12PGRADORA3CHRM1DRD1 | |
| SCHEMBL16800371 | 0.87 | P2RY12 (0.40) | P2RY12PGRADORA3CHRM1DRD1 | |
| SCHEMBL29688154 | 0.87 | P2RY12 (0.49) | P2RY12PGRADORA3CHRM1DRD1 | |
| SCHEMBL1838603 | 0.87 | P2RY12 (0.49) | P2RY12PGRADORA3CHRM1DRD1 | |
| SCHEMBL14900250 | 0.84 | P2RY12 (0.49) | P2RY12PGRADORA3CHRM1DRD1 | |
| SCHEMBL14709129 | 0.83 | P2RY12 (0.40) | P2RY12KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013023511-A1 | TRIAZOLOPYRIMIDINE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | 上海恒瑞医药有限公司 (CN) | 2013-02-21 | — | — | WO | disclosed |