Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.35 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14709024 | 1.00 | GBA1 (0.35) | GBA1FUCA1MGAMCA1CA2 | |
| SCHEMBL3859689 | 0.82 | GBA1 (0.42) | GBA1MGAMCA1CA2GAA | |
| SCHEMBL12858416 | 0.82 | CA2 (0.35) | GBA1MGAMCA1CA2GAA | |
| SCHEMBL7993074 | 0.82 | CA2 (0.35) | GBA1MGAMCA1CA2GAA | |
| SCHEMBL5546534 | 0.82 | CA2 (0.35) | GBA1MGAMCA1CA2GAA | |
| SCHEMBL14215490 | 0.82 | CA2 (0.35) | GBA1MGAMCA1CA2GAA | |
| SCHEMBL9767712 | 0.82 | CA2 (0.35) | GBA1MGAMCA1CA2GAA | |
| SCHEMBL2951506 | 0.82 | GBA1 (0.42) | GBA1MGAMCA1CA2GAA | |
| SCHEMBL7829903 | 0.82 | CA2 (0.35) | GBA1MGAMCA1CA2GAA | |
| SCHEMBL9295329 | 0.82 | CA2 (0.35) | GBA1MGAMCA1CA2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013023511-A1 | TRIAZOLOPYRIMIDINE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | 上海恒瑞医药有限公司 (CN) | 2013-02-21 | — | — | WO | disclosed |