Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.47 |
| ▸ | CHRNB3 | Q05901 | 3/20 | 0.47 |
| ▸ | CHRNA6 | Q15825 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10325650 | 1.00 | HPGD (0.50) | HPGDMAPTCHRNB2CHRNA3CHRNA4 | |
| SCHEMBL12760603 | 1.00 | HPGD (0.50) | HPGDMAPTCHRNB2CHRNA3CHRNA4 | |
| Ammonia Solution, Strong SCHEMBL28469178 | 0.98 | HPGD (0.48) | HPGDMAPTCHRNB2CHRNA3CHRNA4 | |
| Ammonia Solution, Strong SCHEMBL28459544 | 0.98 | HPGD (0.48) | HPGDMAPTCHRNB2CHRNA3CHRNA4 | |
| SCHEMBL26691473 | 0.96 | HPGD (0.47) | HPGDMAPTCHRNB2CHRNA3CHRNA4 | |
| SCHEMBL14068466 | 0.92 | ALDH1A1 (0.57) | HPGDCHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL21087795 | 0.92 | ALDH1A1 (0.57) | HPGDCHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL8056381 | 0.92 | ALDH1A1 (0.57) | HPGDCHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL14197780 | 0.90 | ALDH1A1 (0.61) | HPGDCHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL478741 | 0.88 | ALDH1A1 (0.58) | HPGDMAPTALDH1A1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220247-A1 | LRRK2 INHIBITORS | INTERLINE THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023172737-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2023-09-14 | — | — | WO | disclosed |
| WO-2011056635-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2011-05-12 | — | — | WO | disclosed |