SCHEMBL147102

SCHEMBL147102

[NH]c1cccc2c(S(=O)(=O)O)cccc12

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.60
CYP1A2 P05177 3/20 0.46
AURKA O14965 1/20 0.43
AURKB Q96GD4 1/20 0.43
CDK2 P24941 1/20 0.42
MEN1 O00255 1/20 0.40
NSD2 O96028 1/20 0.40
POLB P06746 1/20 0.40
IDE P14735 1/20 0.40
DUSP3 P51452 1/20 0.40
CCR6 P51684 1/20 0.40
BLM P54132 1/20 0.40
KMT2A Q03164 1/20 0.40
COMT P21964 1/20 0.40
ATIC P31939 2/20 0.39
APEX1 P27695 1/20 0.39
SNCA P37840 2/20 0.38
CHAT P28329 1/20 0.38
CTRB1 P17538 1/20 0.38
ALPL P05186 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10725694 0.89 TTR (0.72) TTRCYP1A2AURKAAURKBCDK2
SCHEMBL158215 0.88 TTR (0.50) TTRCYP1A2AURKAAURKBMEN1
SCHEMBL6242 0.87 TTR (0.75) TTRCYP1A2AURKAAURKBCDK2
SCHEMBL30233642 0.87 TTR (0.75) TTRCYP1A2AURKAAURKBCDK2
SCHEMBL29363198 0.87 TTR (0.75) TTRCYP1A2AURKAAURKBCDK2
Ammonia Solution, Strong SCHEMBL25312340 0.84 TTR (0.72) TTRCYP1A2AURKAAURKBCDK2
Lithium SCHEMBL18420655 0.84 TTR (0.72) TTRCYP1A2AURKAAURKBCDK2
Ammonia Solution, Strong SCHEMBL10954121 0.84 TTR (0.72) TTRCYP1A2AURKAAURKBCDK2
Hydrochloric Acid SCHEMBL7455908 0.84 TTR (0.72) TTRCYP1A2AURKAAURKBCDK2
SCHEMBL460184 0.84 TTR (0.72) TTRCYP1A2AURKAAURKBCDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5021557-A Copper-containing formazan dye, colorfast blue shades on cellulose CIBA-GEIGY CORPORATION (US) 1991-06-04 US claimed
EP-2633088-B1 NON METAL TANNING STAHL INT B V (NL) 2018-09-12 EP disclosed
EP-2633086-B1 NON-METAL TANNING PROCESS STAHL INT B V (NL) 2017-08-16 EP disclosed
EP-2633089-B1 NON METAL TANNING STAHL INT B V (NL) 2017-03-15 EP disclosed
EP-2638181-B1 NON METAL TANNING STAHL INT B V (NL) 2017-02-22 EP disclosed
EP-2638179-B1 NON METAL TANNING STAHL INT BV (NL) 2014-11-26 EP disclosed
EP-2638180-B1 NON METAL TANNING STAHL INT BV (NL) 2014-11-26 EP disclosed
EP-2633087-B1 NON-METAL TANNING PROCESS STAHL INT BV (NL) 2014-09-17 EP disclosed
US-8808398-B2 Non metal tanning STAHL INTERNATIONAL B.V. (NL) 2014-08-19 US disclosed
US-8801804-B2 Non-metal tanning process STAHL INTERNATIONAL B.V. (NL) 2014-08-12 US disclosed
US-20100221502-A1 Anthrapyridone Compound and Salt Thereof, Magenta Ink Composition Containing the Anthrapyridone Compound, and Colored Article NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2010-09-02 US disclosed
US-20100209678-A1 ANTHRAPYRIDONE COMPOUND OR SALT THEREOF, MAGENTA INK COMPOSITION AND COLORED PRODUCT NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2010-08-19 US disclosed
EP-2206747-A1 ANTHRAPYRIDONE COMPOUND, SALT THEREOF, MAGENTA INK COMPOSITION AND COLORED BODY Nippon Kayaku Kabushiki Kaisha (JP) 2010-07-14 EP disclosed
US-7223301-B2 Anthrapyridone compound, water-based magenta ink composition and inkjet recording method NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2007-05-29 US disclosed
US-20060219131-A1 Anthrapyridone compound, aqueous magenta ink composition and inkjet recording method NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2006-10-05 US disclosed
EP-1626069-A1 ANTHRAPYRIDONE COMPOUND, AQUEOUS MAGENTA INK COMPOSITION AND INKJET RECORDING METHOD NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2006-02-15 EP disclosed
EP-1315695-B1 BENZENE TRICARBOXYLIC ACID AMIDES AS INSULIN RECEPTOR ACTIVATORS TELIK INC (US) 2005-07-13 EP disclosed
US-6600069-B2 Insulin receptor kinase activators; treating hyperglycemia; 4-((3,5-bis(N-(4-sulfophenyl)carbamoyl)phenyl)carbonylamino)-benzenesulfonic acid, for example TELIK, INC. 2003-07-29 US disclosed
US-5118826-A Colorfastness CIBA-GEIGY CORPORATION (US) 1992-06-02 US disclosed
US-5021557-A Copper-containing formazan dye, colorfast blue shades on cellulose CIBA-GEIGY CORPORATION (US) 1991-06-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100209678-A1 ANTHRAPYRIDONE COMPOUND OR SALT THEREOF, MAGENTA INK COMPOSITION AND COLORED PRODUCT RB1, ATXN2, ATXN10 TTR 1061/4885CYP1A2 1893/4885AURKA 4/4885
US-20100221502-A1 Anthrapyridone Compound and Salt Thereof, Magenta Ink Composition Containing the Anthrapyridone Compound, and Colored Article ABL1, ATXN2L, ANXA7 TTR 2302/4885CYP1A2 772/4885AURKA 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.