Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 20/20 | 0.50 |
| ▸ | HTR2B | P41595 | 20/20 | 0.50 |
| ▸ | HTR2A | P28223 | 17/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1475261 | 0.90 | HTR2C (0.49) | HTR2CHTR2BHTR2AHTR7 | |
| SCHEMBL1476677 | 0.81 | HTR2C (0.59) | HTR2CHTR2BHTR2AHTR7 | |
| SCHEMBL1477936 | 0.81 | HTR2C (0.53) | HTR2CHTR2BHTR2AHTR7 | |
| SCHEMBL1476212 | 0.77 | HTR2C (0.49) | HTR2CHTR2BHTR2AHTR7 | |
| SCHEMBL1477357 | 0.76 | HTR2A (0.77) | HTR2CHTR2BHTR2AHTR7 | |
| SCHEMBL1475511 | 0.73 | HTR2C (0.61) | HTR2CHTR2BHTR2AHTR7 | |
| SCHEMBL12941713 | 0.73 | HTR2A (0.58) | HTR2CHTR2BHTR2AHTR7 | |
| SCHEMBL2077358 | 0.72 | HTR7 (0.68) | HTR2CHTR2BHTR2AHTR7 | |
| SCHEMBL1476424 | 0.71 | HTR2C (0.72) | HTR2CHTR2BHTR2AHTR7 | |
| SCHEMBL1475870 | 0.70 | HTR2A (0.75) | HTR2CHTR2BHTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1905774-B1 | Fused heterocyclic compounds as serotonin receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2013-02-20 | — | — | EP | disclosed |