Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | ATP2A1 | O14983 | 1/20 | 1.00 |
| ▸ | ATP2A2 | P16615 | 1/20 | 1.00 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17973530 | 1.00 | MAPT (1.00) | MAPTATP2A1ATP2A2ATP2A3KDM4E | |
| Cyclopiazonic Acid SCHEMBL29766832 | 0.82 | KDM4E (1.00) | MAPTATP2A1ATP2A2ATP2A3KDM4E | |
| Cyclopiazonic Acid SCHEMBL15049041 | 0.82 | KDM4E (1.00) | MAPTATP2A1ATP2A2ATP2A3KDM4E | |
| SCHEMBL23752475 | 0.82 | KDM4E (0.76) | MAPTATP2A1ATP2A2ATP2A3KDM4E | |
| SCHEMBL13030305 | 0.79 | KDM4E (0.72) | MAPTATP2A1ATP2A2ATP2A3KDM4E | |
| SCHEMBL20682560 | 0.72 | MAPT (0.56) | MAPTATP2A1ATP2A2ATP2A3KDM4E | |
| SCHEMBL20682561 | 0.69 | MAPT (0.52) | MAPTATP2A1ATP2A2ATP2A3KDM4E | |
| SCHEMBL15592448 | 0.67 | MAPT (0.51) | MAPTATP2A1ATP2A2ATP2A3KDM4E | |
| SCHEMBL26266600 | 0.55 | MEN1 (0.52) | MAPTKDM4EMEN1KMT2ACYP3A4 | |
| SCHEMBL10674181 | 0.55 | KDM4E (0.39) | MAPTATP2A1ATP2A2ATP2A3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103183666-B | Cyclopiazonic acid compound, and preparation and application thereof | INST APPLIED ECOLOGY CAS | 2014-09-17 | — | — | CN | disclosed |
| CN-103183666-A | Cyclopiazonic acid compound, and preparation and application thereof | INST APPLIED ECOLOGY CAS | 2013-07-03 | — | — | CN | disclosed |
| US-20110070579-A1 | POLYKETIDE SYNTHASE-NONRIBOSOMAL PEPTIDE SYNTHETASE GENE | NODA INSTITUTE FOR SCIENTIFIC RESEARCH (JP) | 2011-03-24 | — | — | US | disclosed |
| US-20040197854-A1 | Methods for modifying the production of a polypeptide | NOVOZYMES BIOTECH, INC. | 2004-10-07 | — | — | US | disclosed |
| US-6323002-B1 | GENERATING PREFERENTIAL PROTEIN; CULTURE MUTANT CELLS WHICH CODE PREFERENTIAL PROTEIN, EXPRESS PROTEIN, RECOVER PROTEIN | NOVOZYMES BIOTECH, INC | 2001-11-27 | — | — | US | disclosed |
| EP-0966521-A1 | CELLS HAVING DNA INSERTION MUTATIONS WHICH PRODUCE ALTERED AMOUNTS OF A POLYPEPTIDE | NOVO NORDISK BIOTECH, INC. (US) | 1999-12-29 | — | — | EP | disclosed |
| US-5958727-A | THIS INVENTION RELATES TO METHODS FOR MODIFYING THE PRODUCTION OF A POLYPEPTIDE BY A CELL. | NOVO NORDISK BIOTECH, INC (US) | 1999-09-28 | — | — | US | disclosed |
| WO-1998011203-A1 | CELLS HAVING DNA INSERTION MUTATIONS WHICH PRODUCE ALTERED AMOUNTS OF A POLYPEPTIDE | NOVO NORDISK BIOTECH, INC. (US) | 1998-03-19 | — | — | WO | disclosed |