Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | ATP2A1 | O14983 | 1/20 | 1.00 |
| ▸ | ATP2A2 | P16615 | 1/20 | 1.00 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1471247 | 1.00 | MAPT (1.00) | MAPTATP2A1ATP2A2ATP2A3KDM4E | |
| Cyclopiazonic Acid SCHEMBL29766832 | 0.82 | KDM4E (1.00) | MAPTATP2A1ATP2A2ATP2A3KDM4E | |
| Cyclopiazonic Acid SCHEMBL15049041 | 0.82 | KDM4E (1.00) | MAPTATP2A1ATP2A2ATP2A3KDM4E | |
| SCHEMBL23752475 | 0.82 | KDM4E (0.76) | MAPTATP2A1ATP2A2ATP2A3KDM4E | |
| SCHEMBL13030305 | 0.79 | KDM4E (0.72) | MAPTATP2A1ATP2A2ATP2A3KDM4E | |
| SCHEMBL20682560 | 0.72 | MAPT (0.56) | MAPTATP2A1ATP2A2ATP2A3KDM4E | |
| SCHEMBL20682561 | 0.69 | MAPT (0.52) | MAPTATP2A1ATP2A2ATP2A3KDM4E | |
| SCHEMBL15592448 | 0.67 | MAPT (0.51) | MAPTATP2A1ATP2A2ATP2A3KDM4E | |
| SCHEMBL26266600 | 0.55 | MEN1 (0.52) | MAPTKDM4EMEN1KMT2ACYP3A4 | |
| SCHEMBL10674181 | 0.55 | KDM4E (0.39) | MAPTATP2A1ATP2A2ATP2A3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160220538-A1 | IDENTIFICATION OF SMALL MOLECULES THAT FACILITATE THERAPEUTIC EXON SKIPPING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-08-04 | — | — | US | disclosed |
| US-20160220538-A1 | IDENTIFICATION OF SMALL MOLECULES THAT FACILITATE THERAPEUTIC EXON SKIPPING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160220538-A1 | IDENTIFICATION OF SMALL MOLECULES THAT FACILITATE THERAPEUTIC EXON SKIPPING | RBM17, SMN1; SMN2, SNRPA1 | MAPT 2886/4885ATP2A1 764/4885ATP2A2 1047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.