SCHEMBL1471292

SCHEMBL1471292

NCCNc1ccccc1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.61
CA12 O43570 2/20 0.55
CA9 Q16790 2/20 0.55
CA3 P07451 1/20 0.55
CA4 P22748 1/20 0.55
CA6 P23280 1/20 0.55
CA5A P35218 1/20 0.55
CA7 P43166 1/20 0.55
CA14 Q9ULX7 1/20 0.55
CA5B Q9Y2D0 1/20 0.55
ALDH1A1 P00352 2/20 0.53
TSHR P16473 1/20 0.53
RECQL P46063 1/20 0.53
HSD17B10 Q99714 1/20 0.53
MAPT P10636 4/20 0.50
KDM4E B2RXH2 3/20 0.50
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
THRB P10828 1/20 0.50
ALOX12 P18054 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL29090059 0.89 IDO1 (0.51) IDO1CA12CA9CA3CA4
SCHEMBL13736441 0.86 MAPT (0.57) IDO1CA12CA9CA3CA4
SCHEMBL9577809 0.84 MAPT (0.55) IDO1CA12CA9CA3CA4
SCHEMBL5362698 0.82 MAPT (0.53) IDO1CA12CA9CA3CA4
SCHEMBL28927027 0.82 MAPT (0.53) IDO1CA12CA9CA3CA4
SCHEMBL14895469 0.81 IDO1 (0.44) IDO1CA12CA9CA3CA4
SCHEMBL2204571 0.80 KDM4E (0.52) IDO1CA12CA9CA3CA4
SCHEMBL3081628 0.80 MEN1 (0.53) IDO1CA12CA9CA3CA4
SCHEMBL3081625 0.80 MEN1 (0.53) IDO1CA12CA9CA3CA4
SCHEMBL8751587 0.78 MAPT (0.50) IDO1CA12CA9CA3CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118307410-A Preparation method of chiral secondary alcohol compound 武汉大学 2024-07-09 CN claimed
CN-118063389-A Process for preparing imidazole derivatives 远大医学营养科学(武汉)有限公司 2024-05-24 CN claimed
CN-113372238-B Imine compound and its synthesis method and use 上海科技大学 2022-09-23 CN claimed
CN-113372238-A Imine compound and its synthesis method and use 上海科技大学 2021-09-10 CN claimed
US-4481141-A COLOR PHOTOGRAPHJY, DIFFUSION TRANSFER EASTMAN KODAK COMPANY (US) 1984-11-06 US claimed
US-4418131-A Photographic products and processes employing novel nondiffusible yellow dye-releasing compounds and precursors thereof EASTMAN KODAK COMPANY (US) 1983-11-29 US claimed
US-4407931-A DIFFUSION TRANSFER EASTMAN KODAK COMPANY (US) 1983-10-04 US claimed
US-12037405-B2 Anti-CD70 antibody drug conjugates AMBRX, INC. 2024-07-16 US disclosed
CN-118307410-A Preparation method of chiral secondary alcohol compound 武汉大学 2024-07-09 CN disclosed
CN-118063389-A Process for preparing imidazole derivatives 远大医学营养科学(武汉)有限公司 2024-05-24 CN disclosed
CN-117280489-A Positive electrode mixture, positive electrode, and secondary battery 大金工业株式会社 2023-12-22 CN disclosed
CN-117223122-A Positive electrode mixture, positive electrode, and secondary battery 大金工业株式会社 2023-12-12 CN disclosed
CN-117223123-A Positive electrode mixture, positive electrode, and secondary battery 大金工业株式会社 2023-12-12 CN disclosed
EP-0097849-B1 PHOTOGRAPHIC RECORDING MATERIAL EMPLOYING A NONDIFFUSIBLE YELLOW DYE-RELEASING COMPOUND EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1986-09-10 EP disclosed
EP-0135017-A1 Process for the stabilisation of poly(phenylene ether) solutions BASF Aktiengesellschaft (DE) 1985-03-27 EP disclosed
US-4481141-A COLOR PHOTOGRAPHJY, DIFFUSION TRANSFER EASTMAN KODAK COMPANY (US) 1984-11-06 US disclosed
EP-0116955-A2 Complexes of (1,2-diphenyl-ethylene diamine) platinum (II) Degussa Aktiengesellschaft (DE) 1984-08-29 EP disclosed
EP-0097849-A2 Photographic recording material employing a nondiffusible yellow dye-releasing compound EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-01-11 EP disclosed
US-4418131-A Photographic products and processes employing novel nondiffusible yellow dye-releasing compounds and precursors thereof EASTMAN KODAK COMPANY (US) 1983-11-29 US disclosed
US-4407931-A DIFFUSION TRANSFER EASTMAN KODAK COMPANY (US) 1983-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12037405-B2 Anti-CD70 antibody drug conjugates CD74, CD63, CD47 IDO1 1101/4885CA12 875/4885CA9 1209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.