Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13736441 | 0.86 | MAPT (0.57) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL9577809 | 0.84 | MAPT (0.55) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL28927027 | 0.82 | MAPT (0.53) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9442781 | 0.80 | CA12 (0.36) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL11401614 | 0.80 | IDO1 (0.54) | MAPTKDM4EALDH1A1CA12CA9 | |
| SCHEMBL2204571 | 0.80 | KDM4E (0.52) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL1471292 | 0.78 | IDO1 (0.61) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL7838711 | 0.78 | KDM4E (0.50) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL1404068 | 0.78 | MAPT (0.50) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL1955931 | 0.78 | IDO1 (0.61) | MAPTKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592396-B1 | BENZOXAZINE DYES | BRISTOL MYERS SQUIBB CO (US) | 1997-04-16 | — | — | EP | disclosed |
| EP-0592396-A1 | BENZOXAZINE DYES. | BRISTOL MYERS SQUIBB CO (US) | 1994-04-20 | — | — | EP | disclosed |
| EP-0592396-A4 | BENZOXAZINE DYES. | BRISTOL MYERS SQUIBB CO (US) | 1992-09-28 | — | — | EP | disclosed |
| US-5118323-A | Hair dyes | CLAIROL, INC. | 1992-06-02 | — | — | US | disclosed |
| US-5055110-A | Hair dyes | CLAIROL INCORPORATED (US) | 1991-10-08 | — | — | US | disclosed |
| WO-1991007394-A1 | BENZOXAZINE DYES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-05-30 | — | — | WO | disclosed |