Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 15/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 10/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14713166 | 0.89 | KDR (0.44) | KDRPDGFRBPTGDR2PTGS1PTGS2 | |
| SCHEMBL14713208 | 0.89 | KDR (0.46) | KDRPDGFRBPTGDR2 | |
| SCHEMBL834682 | 0.88 | KDR (0.45) | KDRPDGFRBPTGDR2PTGS1PTGS2 | |
| SCHEMBL14713211 | 0.88 | KDR (0.48) | KDRPDGFRBPTGS2 | |
| SCHEMBL1479033 | 0.87 | KDR (0.49) | KDRPDGFRBMAPTPTGDR2 | |
| SCHEMBL834903 | 0.87 | KDR (0.40) | KDRPDGFRBMAPTSAE1UBA2 | |
| SCHEMBL833449 | 0.86 | KDR (0.44) | KDRPDGFRBMAPTSAE1UBA2 | |
| SCHEMBL834498 | 0.86 | KDR (0.52) | KDRPDGFRBPTGDR2PTGS2 | |
| SCHEMBL836827 | 0.85 | MAPT (0.42) | KDRPDGFRBMAPTSAE1UBA2 | |
| SCHEMBL834677 | 0.85 | KDR (0.43) | KDRPDGFRBMAPTPTGDR2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383825-B2 | Kinase inhibitors | ALLERGAN, INC. (US) | 2013-02-26 | — | — | US | disclosed |