Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 17/20 | 0.53 |
| ▸ | HTR2B | P41595 | 11/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2572371 | 0.89 | HTR2C (0.50) | HTR2CHTR2BHTR6HTR2AMEN1 | |
| SCHEMBL2562086 | 0.86 | HTR2C (0.52) | HTR2CHTR2BHTR2AMEN1GAA | |
| SCHEMBL692986 | 0.83 | HTR2C (0.46) | HTR2CHTR2BHTR2AMEN1GAA | |
| SCHEMBL2575196 | 0.81 | HTR2C (0.57) | HTR2CHTR2BHTR6HTR2AMEN1 | |
| SCHEMBL2016944 | 0.80 | HTR2C (0.48) | HTR2CHTR2BHTR6HTR2AALDH1A1 | |
| SCHEMBL2017936 | 0.79 | HTR2C (0.60) | HTR2CHTR2BHTR2A | |
| SCHEMBL14714340 | 0.79 | HTR2C (0.60) | HTR2CHTR2BHTR2A | |
| SCHEMBL2566042 | 0.79 | HTR7 (0.44) | HTR2CHTR2BHTR2AMEN1GAA | |
| SCHEMBL2020219 | 0.78 | HTR2C (0.51) | HTR2CHTR2BHTR6HTR2AHTR1A | |
| SCHEMBL2572284 | 0.78 | HTR2C (0.51) | HTR2CHTR2BHTR6HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560973-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | Abbvie Inc. (US) | 2013-02-27 | — | — | EP | disclosed |