Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.60 |
| ▸ | MTNR1A | P48039 | 14/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | NQO2 | P16083 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL827963 | 0.79 | HTR2A (0.70) | HTR2AMTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL12013659 | 0.79 | HTR2A (0.65) | HTR2AMTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL14714813 | 0.78 | HTR2A (0.68) | HTR2AMTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL124465 | 0.78 | HTR2A (0.68) | HTR2AMTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL29594789 | 0.78 | HTR2A (0.68) | HTR2AMTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL17444606 | 0.78 | HTR2A (0.68) | HTR2AMTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL1882845 | 0.78 | HTR2A (0.68) | HTR2AMTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL5250295 | 0.77 | ACP3 (0.49) | MTNR1ANQO2 | |
| SCHEMBL13792236 | 0.77 | HTR2A (0.78) | HTR2AMTNR1AMTNR1BHTR2CHTR2B | |
| Bromide SCHEMBL15661932 | 0.77 | HTR2A (0.67) | HTR2AMTNR1AMTNR1BHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562151-A1 | Processes for the preparation of agomelatine and its intermediates | Dr. Reddy's Laboratories Ltd. (IN) | 2013-02-27 | — | — | EP | disclosed |
| EP-2562151-A1 | Processes for the preparation of agomelatine and its intermediates | Dr. Reddy's Laboratories Ltd. (IN) | 2013-02-27 | — | — | EP | disclosed |