Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1171268 | 0.81 | ALDH1A1 (0.52) | ACP3ALDH1A1CYP1A2CYP2C19CYP2D6 | |
| Nitric Acid SCHEMBL9872877 | 0.79 | ACP3 (0.50) | ACP3ALDH1A1CYP1A2CYP2C19MTNR1A | |
| SCHEMBL8957420 | 0.77 | NQO2 (0.46) | ACP3ALDH1A1CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL3047898 | 0.77 | CYP1A2 (0.62) | ACP3ALDH1A1CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL14714873 | 0.77 | HTR2A (0.60) | MTNR1ANQO2 | |
| SCHEMBL28249204 | 0.77 | CYP3A4 (0.51) | ALDH1A1CYP1A2CYP2C19CYP2D6TDP1 | |
| SCHEMBL28344036 | 0.75 | ALDH1A1 (0.43) | ALDH1A1CYP1A2CYP2C19CYP2D6CYP3A4 | |
| SCHEMBL11523496 | 0.75 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2C19CYP2D6TDP1 | |
| SCHEMBL28749492 | 0.75 | ALDH1A1 (0.62) | ALDH1A1CYP1A2CYP2C19CYP3A4POLB | |
| SCHEMBL3230471 | 0.75 | ALDH1A1 (0.51) | ALDH1A1CYP1A2CYP2C19CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113711007-A | Method for determining generation source of fine particles in atmosphere | 株式会社岛津制作所 | 2021-11-26 | — | — | CN | claimed |
| CN-113711007-A | Method for determining generation source of fine particles in atmosphere | 株式会社岛津制作所 | 2021-11-26 | — | — | CN | disclosed |
| CN-111087957-A | Adhesive composition, cured product, optical member, touch panel, liquid crystal sealing agent, and liquid crystal display unit | 日本化药株式会社 | 2020-05-01 | — | — | CN | disclosed |
| CN-106243052-B | Substituted heterocyclic compounds, process for their preparation and their use | 广东东阳光药业有限公司 | 2020-01-21 | — | — | CN | disclosed |
| CN-105579112-B | The gas absorbent solution and technique of reversible optical drive | 联邦科学及工业研究组织 | 2018-11-02 | — | — | CN | disclosed |
| CN-106243052-A | Substituted heterocyclic compound and its production and use | 广东东阳光药业有限公司 | 2016-12-21 | — | — | CN | disclosed |
| EP-1361225-B1 | COMPOUNDS SUBSTITUTED WITH BICYCLIC AMINO GROUPS | SANKYO CO (JP) | 2007-11-07 | — | — | EP | disclosed |
| US-7122666-B2 | Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses | SANKYO COMPANY, LIMITED (JP) | 2006-10-17 | — | — | US | disclosed |
| US-7091352-B2 | Compounds substituted with bicyclic amino groups | SANKYO COMPANY, LIMITED (JP) | 2006-08-15 | — | — | US | disclosed |
| US-20060128756-A1 | Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses | SANKYO COMPANY, LIMITED (JP) | 2006-06-15 | — | — | US | disclosed |
| US-6511978-B1 | For treating cancer, restenosis, atherosclerosis or viral infections | LG LIFE SCIENCES, LTD. (KR) | 2003-01-28 | — | — | US | disclosed |
| EP-1243589-A1 | Heteroaryl-substituted pyrrole derivates, their preparation and their therapeutic uses | Sankyo Company Limited (JP) | 2002-09-25 | — | — | EP | disclosed |
| EP-1070711-A2 | Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |
| CN-1022319-C | 1, 2, 3, 4-tetrahydronaphthalene derivatives, process for their preparation and their use as medicaments | MERRELL DOW PHARMA (US) | 1993-10-06 | — | — | CN | disclosed |
| EP-0378456-B1 | TETRALIN DERIVATIVES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5106861-A | Method of using certain tetralin derivatives to produce analgesic relief | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-04-21 | — | — | US | disclosed |
| US-5041673-A | Aminopeptidase inhibitors, immunomodulators, analgesics | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-08-20 | — | — | US | disclosed |
| EP-0381902-A1 | Tetralin derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-08-16 | — | — | EP | disclosed |
| CN-1044460-A | Novel 1,2,3,4-tetralin derivative | MERRELL DOW PHARMA (US) | 1990-08-08 | — | — | CN | disclosed |
| EP-0378456-A1 | Tetralin derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-07-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128756-A1 | Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses | IL2, IL1A, IL1B | ACP3 2593/4885ALDH1A1 871/4885CYP1A2 665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.