Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14714600 | 0.76 | NPC1 (0.46) | HDAC1HDAC6NPC1RAB9A | |
| SCHEMBL19102622 | 0.69 | HDAC2 (0.39) | HDAC1HDAC6RAB9ARARB | |
| SCHEMBL19102817 | 0.67 | GABRP (0.36) | HDAC6 | |
| SCHEMBL14714891 | 0.66 | — | — | |
| SCHEMBL17435483 | 0.66 | HDAC2 (0.34) | HDAC6 | |
| SCHEMBL5391734 | 0.66 | HDAC1 (0.49) | HDAC1HDAC6HSD17B1KDM1A | |
| SCHEMBL6668052 | 0.65 | EGLN1 (0.51) | HSD17B1KDM1AALDH1A1 | |
| SCHEMBL19102623 | 0.65 | ACACB (0.35) | — | |
| SCHEMBL19102813 | 0.65 | ACACB (0.37) | HDAC1HDAC6RARB | |
| SCHEMBL9426036 | 0.64 | GAA (0.44) | HDAC1HDAC6NPC1RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562155-A1 | NOVEL HYDROXAMIC ACID DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2013-02-27 | — | — | EP | disclosed |