SCHEMBL14714958

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14715017	0.90	HPGD (0.55)	RAB9ASMN1; SMN2NPC1KMT2AALDH1A1
	SCHEMBL14714750	0.86	MEN1 (0.57)	RAB9ASMN1; SMN2NPC1KMT2AMEN1
	SCHEMBL14715199	0.85	NPC1 (0.51)	RAB9ASMN1; SMN2NPC1KMT2AALDH1A1
	SCHEMBL14714981	0.85	ANPEP (0.49)	NPC1MMP1MMP3
	SCHEMBL14714742	0.83	NPC1 (0.49)	RAB9ASMN1; SMN2NPC1KMT2AMEN1
	SCHEMBL14715049	0.82	PPARG (0.51)	MMP1MMP3
	SCHEMBL14714497	0.82	PPARG (0.51)	RAB9ASMN1; SMN2NPC1MMP1
	SCHEMBL14714895	0.82	PPARG (0.46)	RAB9ANPC1KMT2AMEN1MMP1
	SCHEMBL14714574	0.81	PPARG (0.46)	NPC1ALDH1A1LMNA
	SCHEMBL14714713	0.81	USP2 (0.46)	NPC1HSD17B10MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.