Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.31 |
| ▸ | VCP | P55072 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6047877 | 0.81 | ALDH1A1 (0.38) | HIF1AALDH1A1VCAM1ATMTDP1 | |
| SCHEMBL27807540 | 0.79 | TSHR (0.39) | HIF1AALDH1A1TDP1TP53CYP3A4 | |
| SCHEMBL28616041 | 0.76 | ALDH1A1 (0.35) | HIF1AALDH1A1VCAM1ATMTDP1 | |
| SCHEMBL27841020 | 0.75 | ALDH1A1 (0.34) | HIF1AALDH1A1VCAM1ATMTDP1 | |
| SCHEMBL146415 | 0.72 | ATM (0.35) | HIF1AALDH1A1VCAM1ATMTDP1 | |
| SCHEMBL2350187 | 0.70 | TSHR (0.38) | HIF1AALDH1A1ATMTDP1TSHR | |
| SCHEMBL58486 | 0.69 | TSHR (0.46) | ALDH1A1TDP1TSHRSMN1; SMN2LMNA | |
| SCHEMBL4926477 | 0.67 | KDM4E (0.34) | ALDH1A1ATMTDP1CASP6POLB | |
| SCHEMBL7513494 | 0.66 | ALDH1A1 (0.48) | HIF1AALDH1A1VCAM1ATMTDP1 | |
| SCHEMBL28195141 | 0.65 | ATM (0.40) | HIF1AALDH1A1VCAM1ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2532663-B1 | Naphthalenetetracarboxylic acid derivatives and their use as semiconductors | BASF SE (DE) | 2016-03-16 | — | — | EP | claimed |
| EP-2532663-A1 | Naphthalenecarboxylic acid derivatives and their use as semiconductors | BASF SE (DE) | 2012-12-12 | — | — | EP | claimed |
| EP-1280753-A1 | PROCESS FOR PREPARATION OF R-1-(ARYLOXY)PROPAN-2-OL | Rhodia/Chirex, Inc. (US) | 2003-02-05 | — | — | EP | claimed |
| US-6448449-B2 | RING OPENING OF (R)-PROPYLENE OXIDE WITH ARYLTRIMETHYLSILYL ETHER IN THE PRESENCE OF AN OPTICALLY ACTIVE CATALYST; REACTING WITH AN ALCOHOL IN THE PRESENCE OF AN ACID; REACTING THE REGIOISOMERIC MIXTURE WITH A TRIARYLMETHYL HALILE; | RHODIA CHIREX, INC. | 2002-09-10 | — | — | US | claimed |
| US-20020007090-A1 | Process for preparation of (R)-1- (aryloxy)propan-2-ol | RHODIA CHIREX, INC. | 2002-01-17 | — | — | US | claimed |
| WO-2001081286-A1 | PROCESS FOR PREPARATION OF R-1-(ARYLOXY)PROPAN-2-OL | RHODIA/CHIREX, INC. (US) | 2001-11-01 | — | — | WO | claimed |
| US-20170174676-A1 | CHLORINATED NAPTHALENETETRACARBOXYLIC ACID DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN ORGANIC ELECTRONICS | BASF SE (DE) | 2017-06-22 | — | — | US | disclosed |
| US-9583719-B2 | Carbazolocarbazol-bis(dicarboximides) and their use as semiconductors | BASF SE (DE) | 2017-02-28 | — | — | US | disclosed |
| US-9512354-B2 | Chlorinated naphthalenetetracarboxylic acid derivatives, preparation thereof and use thereof in organic electronics | BASF SE (DE) | 2016-12-06 | — | — | US | disclosed |
| US-9385326-B2 | Triangulene oligomers and polymers and their use as hole conducting material | BASF SE (DE) | 2016-07-05 | — | — | US | disclosed |
| EP-2742112-B1 | CARBAZOLOCARBAZOL-BIS(DICARBOXIMIDES) AND THEIR USE AS SEMICONDUCTORS | BASF SE (DE) | 2016-05-18 | — | — | EP | disclosed |
| EP-2532663-B1 | Naphthalenetetracarboxylic acid derivatives and their use as semiconductors | BASF SE (DE) | 2016-03-16 | — | — | EP | disclosed |
| EP-2181172-B1 | HALOGEN-CONTAINING PERYLENETETRACARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF | BASF SE (DE) | 2016-02-24 | — | — | EP | disclosed |
| WO-2007074137-A1 | NAPHTHALENETETRACARBOXYLIC ACID DERIVATIVES AND THEIR USE AS SEMICONDUCTORS | BASF SE (DE) | 2007-07-05 | — | — | WO | disclosed |
| EP-1719770-A2 | Quinoline derivatives as antibacterials | SMITHKLINE BEECHAM PLC (GB) | 2006-11-08 | — | — | EP | disclosed |
| EP-1320529-B1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2006-05-24 | — | — | EP | disclosed |
| EP-1280753-A1 | PROCESS FOR PREPARATION OF R-1-(ARYLOXY)PROPAN-2-OL | Rhodia/Chirex, Inc. (US) | 2003-02-05 | — | — | EP | disclosed |
| US-6448449-B2 | RING OPENING OF (R)-PROPYLENE OXIDE WITH ARYLTRIMETHYLSILYL ETHER IN THE PRESENCE OF AN OPTICALLY ACTIVE CATALYST; REACTING WITH AN ALCOHOL IN THE PRESENCE OF AN ACID; REACTING THE REGIOISOMERIC MIXTURE WITH A TRIARYLMETHYL HALILE; | RHODIA CHIREX, INC. | 2002-09-10 | — | — | US | disclosed |
| US-20020007090-A1 | Process for preparation of (R)-1- (aryloxy)propan-2-ol | RHODIA CHIREX, INC. | 2002-01-17 | — | — | US | disclosed |
| WO-2001081286-A1 | PROCESS FOR PREPARATION OF R-1-(ARYLOXY)PROPAN-2-OL | RHODIA/CHIREX, INC. (US) | 2001-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020007090-A1 | Process for preparation of (R)-1- (aryloxy)propan-2-ol | TOP1, POLN, RIF1 | HIF1A 4306/4885ALDH1A1 180/4885VCAM1 341/4885 |
| US-20170174676-A1 | CHLORINATED NAPTHALENETETRACARBOXYLIC ACID DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN ORGANIC ELECTRONICS | SLCO2A1, SLCO2B1, SLC43A3 | HIF1A 4066/4885ALDH1A1 1455/4885VCAM1 3738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.