Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2899979 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TSHRHTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL2896615 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TSHRHTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL1664842 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TSHRHTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL2900095 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TSHRHTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL2894583 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TSHRHTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL25207012 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TSHRHTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL135809 | 0.94 | ALDH1A1 (0.47) | ALDH1A1TSHRHTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL2894592 | 0.93 | EPHX2 (0.46) | ALDH1A1TSHREPHX2 | |
| SCHEMBL2902670 | 0.93 | EPHX2 (0.46) | ALDH1A1TSHREPHX2 | |
| SCHEMBL14715663 | 0.93 | EPHX2 (0.46) | ALDH1A1TSHREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197866-B1 | HYDROXYMETHYLFURFURAL ETHERS FROM SUGARS AND HIGHER ALCOHOLS | FURANIX TECHNOLOGIES BV (NL) | 2013-02-27 | — | — | EP | claimed |