Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785172 | 0.80 | TSHR (0.46) | TSHRLMNASOAT1 | |
| SCHEMBL13130757 | 0.74 | TSHR (0.39) | TSHRLMNA | |
| SCHEMBL288698 | 0.74 | TSHR (0.53) | TSHRLMNASOAT1 | |
| SCHEMBL3483417 | 0.72 | TSHR (0.52) | TSHRLMNA | |
| SCHEMBL8437495 | 0.72 | TSHR (0.60) | TSHRLMNA | |
| SCHEMBL16087758 | 0.72 | TSHR (0.46) | TSHRLMNASOAT1 | |
| Propane SCHEMBL22462424 | 0.72 | TSHR (0.46) | TSHRLMNASOAT1 | |
| SCHEMBL13133071 | 0.72 | TSHR (0.46) | TSHRLMNASOAT1 | |
| SCHEMBL11055977 | 0.71 | TSHR (0.36) | TSHRLMNA | |
| SCHEMBL16212808 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1898951-B1 | PHARMACEUTICAL PREPARATION CONTAINING AN ANGIOTENSIN II RECEPTOR ANTAGONIST AND A CALCIUM CHANNEL BLOCKER | DAIICHI SANKYO CO LTD (JP) | 2013-02-27 | — | — | EP | disclosed |