Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GALR3 | O60755 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL22462424 | 0.82 | TSHR (0.46) | TSHRLMNAALDH1A1TDP1SOAT1 | |
| SCHEMBL14715672 | 0.80 | TSHR (0.41) | TSHRLMNASOAT1 | |
| SCHEMBL288698 | 0.79 | TSHR (0.53) | TSHRLMNAALDH1A1SOAT1HCAR2 | |
| SCHEMBL3483417 | 0.77 | TSHR (0.52) | TSHRLMNAALDH1A1HCAR2CHRM2 | |
| SCHEMBL8437495 | 0.77 | TSHR (0.60) | TSHRLMNAALDH1A1TDP1HCAR2 | |
| SCHEMBL11424212 | 0.77 | — | — | |
| SCHEMBL5220953 | 0.76 | — | — | |
| SCHEMBL3706557 | 0.75 | TSHR (0.57) | TSHRLMNAALDH1A1TDP1HCAR2 | |
| SCHEMBL8848426 | 0.74 | SOAT1 (0.68) | TSHRLMNAALDH1A1SOAT1HCAR2 | |
| SCHEMBL6471616 | 0.73 | TSHR (0.48) | TSHRLMNAALDH1A1TDP1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008079387-A1 | CATECHOL PROTECTED LEVODOPA DIESTER PRODRUGS, COMPOSITIONS, AND METHODS OF USE | XENOPORT, INC. (US) | 2008-07-03 | — | — | WO | disclosed |