Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 11/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27900170 | 0.98 | EPHX2 (0.51) | EPHX2FAAHNAMPTDRD2DRD3 | |
| SCHEMBL3079841 | 0.88 | DRD3 (0.55) | EPHX2NAMPTDRD2DRD3 | |
| SCHEMBL3088045 | 0.88 | DRD3 (0.55) | EPHX2NAMPTDRD2DRD3 | |
| SCHEMBL3959408 | 0.88 | EPHX2 (0.50) | EPHX2FAAHNAMPTDRD2DRD3 | |
| SCHEMBL3087492 | 0.87 | DRD3 (0.51) | EPHX2NAMPTDRD2DRD3 | |
| SCHEMBL3966402 | 0.87 | DRD2 (0.58) | EPHX2DRD2DRD3 | |
| SCHEMBL3074454 | 0.85 | DRD2 (0.56) | EPHX2NAMPTDRD2DRD3 | |
| SCHEMBL3074452 | 0.85 | DRD2 (0.56) | EPHX2NAMPTDRD2DRD3 | |
| SCHEMBL14715683 | 0.84 | DRD3 (0.43) | DRD2DRD3 | |
| SCHEMBL3079529 | 0.84 | EPHX2 (0.60) | EPHX2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079693-B1 | ETHER DERIVATIVES DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS | HOFFMANN LA ROCHE (CH) | 2013-02-27 | — | — | EP | claimed |