⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL723881 | 0.82 | — | — | |
| SCHEMBL7878 | 0.79 | CYP1A2 (0.42) | — | |
| Hydrochloric Acid SCHEMBL20817034 | 0.78 | CYP1A2 (0.41) | — | |
| SCHEMBL28862327 | 0.78 | CYP1A2 (0.41) | — | |
| Hydrochloric Acid SCHEMBL221473 | 0.78 | CYP1A2 (0.41) | — | |
| Water SCHEMBL27520041 | 0.78 | CYP1A2 (0.41) | — | |
| SCHEMBL14715713 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL28158071 | 0.76 | CYP1A2 (0.39) | — | |
| SCHEMBL28601512 | 0.75 | TRPA1 (0.33) | — | |
| Carbimide SCHEMBL27821215 | 0.74 | CYP1A2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230341406-A1 | MEANS AND METHODS FOR TREATING ANGIOGENESIS-RELATED DISEASES | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2023-10-26 | — | — | US | disclosed |
| EP-4215206-A1 | PROTEIN COMPRISING NC-1 FOR TREATING ANGIOGENESIS-RELATED DISEASES | Deutsches Krebsforschungszentrum (DE) | 2023-07-26 | — | — | EP | disclosed |
| EP-2747775-B1 | PROTEIN COMPRISING NC-1 FOR TREATING ANGIOGENESIS-RELATED DISEASES | DEUTSCHES KREBSFORSCH (DE) | 2023-03-22 | — | — | EP | disclosed |
| EP-2561888-A1 | Protein comprising NC-1 for treating angiogenesis-related diseases | Deutsches Krebsforschungszentrum (DE) | 2013-02-27 | — | — | EP | disclosed |