SCHEMBL14715728

SCHEMBL14715728

NC1(NC(=O)C(=O)O)CC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM5B Q9UGL1 1/20 0.36
HIF1A Q16665 1/20 0.32
GRM4 Q14833 6/20 0.31
CYP1A2 P05177 3/20 0.31
CYP2C19 P33261 3/20 0.31
GRM2 Q14416 2/20 0.31
GRM3 Q14832 2/20 0.31
ALOX15 P16050 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
GRM8 O00222 2/20 0.31
GRM6 O15303 2/20 0.31
LMNA P02545 1/20 0.31
GRM5 P41594 1/20 0.31
MTOR P42345 1/20 0.31
GRM1 Q13255 1/20 0.31
PLCB1 Q9NQ66 1/20 0.31
SLC6A12 P48065 1/20 0.31
SLC6A11 P48066 1/20 0.31
TSHR P16473 1/20 0.31
ALDH1A1 P00352 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8096790 0.70
SCHEMBL15232657 0.68
SCHEMBL13839062 0.67
SCHEMBL477423 0.67 HDAC4 (0.38) CYP1A2CYP2C19LMNATSHRALDH1A1
SCHEMBL22302657 0.66 ALDH1A1 (0.32) CYP2C19TSHRALDH1A1
SCHEMBL25590181 0.65 ALDH1A1 (0.32) ALDH1A1MEN1KMT2AKDM4E
Hydrochloric Acid SCHEMBL28026349 0.64 MEN1 (0.34) TSHRMEN1KMT2ACYP2C9KDM4E
SCHEMBL28110483 0.63 CYP1A2 (0.34) GRM4CYP1A2CYP2C19GRM2GRM3
SCHEMBL15062781 0.62 ALDH1A1 (0.39) CYP1A2CYP2C19LMNATSHRALDH1A1
SCHEMBL30877174 0.60 EPHX2 (0.37) KDM5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8658570-B2 Use of anthranilamide derivatives for controlling insects and spider mites by drenching, soil mixing, furrow treatment, drip application, soil, stem or flower injection, in hydroponic systems, by planting hole treatment or dip application, floating or seedbox application or by treating seed, and also for enhancing the stress tolerance of plants to abiotic stress BAYER CROPSCIENCE AG (DE) 2014-02-25 US claimed
EP-4230621-A1 SUBSTITUTED N-BENZOIC ACID URACILS, THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS Bayer AG (DE) 2023-08-23 EP disclosed
EP-4230620-A1 SUBSTITUTED N-AMINO-N-BENZOIC ACID URACILS, THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS Bayer Aktiengesellschaft (DE) 2023-08-23 EP disclosed
CN-116368129-A 1- (pyridinyl) -5-azinylpyrazole derivatives and their use for controlling harmful plant growth 拜耳公司 2023-06-30 CN disclosed
EP-2964023-B1 USE OF N-(2-METHOXYBENZOYL)-4-[METHYLAMINOCARBONYL)AMINO]BENZENESULFONAMIDE IN COMBINATION WITH AN INSECTICIDE OR FUNGICIDE FOR IMPROVING PLANT YIELD BAYER CROPSCIENCE AG (DE) 2019-08-07 EP disclosed
EP-2964027-B1 USE OF COMBINATIONS COMPRISING CLOQUINTOCET-MEXYL FOR IMPROVING PLANT YIELD BAYER CROPSCIENCE AG (DE) 2019-04-24 EP disclosed
EP-2755472-B1 USE OF CYPROSULFAMIDE FOR IMPROVING PLANT YIELD BAYER IP GMBH (DE) 2016-08-31 EP disclosed
EP-2964027-A1 USE OF QUINOLINE DERIVATIVES FOR IMPROVING PLANT YIELD Bayer CropScience AG (DE) 2016-01-13 EP disclosed
EP-2964023-A1 USE OF ACYLSULFONAMIDES FOR IMPROVING PLANT YIELD Bayer CropScience Aktiengesellschaft (DE) 2016-01-13 EP disclosed
WO-2014135468-A1 USE OF ACYLSULFONAMIDES FOR IMPROVING PLANT YIELD BAYER CROPSCIENCE AG (DE) 2014-09-12 WO disclosed
WO-2014135481-A1 USE OF QUINOLINE DERIVATIVES FOR IMPROVING PLANT YIELD BAYER CROPSCIENCE AG (DE) 2014-09-12 WO disclosed
EP-2755472-A1 USE OF ACYLSULFONAMIDES FOR IMPROVING PLANT YIELD Bayer Intellectual Property GmbH (DE) 2014-07-23 EP disclosed
EP-2755484-A1 USE OF 5-PHENYL- OR 5-BENZYL-2 ISOXAZOLINE-3 CARBOXYLATES FOR IMPROVING PLANT YIELD Bayer Intellectual Property GmbH (DE) 2014-07-23 EP disclosed
EP-2755471-A1 USE OF PHENYLPYRAZOLIN-3-CARBOXYLATES FOR IMPROVING PLANT YIELD Bayer Intellectual Property GmbH (DE) 2014-07-23 EP disclosed
WO-2013037958-A1 USE OF PHENYLPYRAZOLIN-3-CARBOXYLATES FOR IMPROVING PLANT YIELD BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-03-21 WO disclosed
WO-2013037956-A1 USE OF 5-PHENYL- OR 5-BENZYL-2 ISOXAZOLINE-3 CARBOXYLATES FOR IMPROVING PLANT YIELD BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-03-21 WO disclosed
WO-2013037955-A1 USE OF ACYLSULFONAMIDES FOR IMPROVING PLANT YIELD BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-03-21 WO disclosed
EP-2561759-A1 Fluoroalkyl-substituted 2-amidobenzimidazoles and their effect on plant growth Bayer Cropscience AG (DE) 2013-02-27 EP disclosed