Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2115758 | 0.84 | ADRB1 (0.63) | ADRB1HTR2AHTR2BSIGMAR1 | |
| SCHEMBL2114251 | 0.82 | ADRB1 (0.66) | ADRB1HTR2AHTR2BSIGMAR1 | |
| SCHEMBL2116102 | 0.81 | ADRB1 (0.61) | ADRB1HTR2AHTR2BSIGMAR1 | |
| SCHEMBL2117325 | 0.79 | ADRB1 (0.64) | ADRB1HTR2AHTR2BSIGMAR1 | |
| SCHEMBL2115398 | 0.79 | ADRB1 (0.64) | ADRB1HTR2AHTR2BSIGMAR1 | |
| SCHEMBL2116792 | 0.78 | ADRB1 (0.56) | ADRB1HTR2AHTR2BSIGMAR1 | |
| SCHEMBL2118281 | 0.78 | HTR2B (0.70) | ADRB1HTR2AHTR2BSIGMAR1 | |
| SCHEMBL2116255 | 0.78 | ADRB1 (0.80) | ADRB1HTR2AHTR2BSIGMAR1 | |
| SCHEMBL2117874 | 0.78 | ADRB1 (0.66) | ADRB1HTR2AHTR2BSIGMAR1 | |
| SCHEMBL3407135 | 0.78 | ADRB1 (0.76) | ADRB1HTR2AHTR2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150550-B1 | NOVEL CARBAMOYLOXY ARYL ALKAN ARYLPIPERAZINE COMPOUND, PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUND AND METHOD FOR TREATING PAIN, ANXIETY AND DEPRESSION BY ADMINISTERING THE COMPOUND | SK BIOPHARMACEUTICALS CO LTD (KR) | 2013-02-27 | — | — | EP | disclosed |