Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 17/20 | 0.60 |
| ▸ | HTR2A | P28223 | 16/20 | 0.60 |
| ▸ | DRD2 | P14416 | 8/20 | 0.51 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3081406 | 1.00 | DRD3 (0.60) | DRD3HTR2ADRD2UTS2RPOLB | |
| SCHEMBL4076666 | 0.93 | DRD2 (0.56) | DRD3HTR2ADRD2 | |
| SCHEMBL4071895 | 0.90 | DRD3 (0.53) | DRD3HTR2ADRD2UTS2RPOLB | |
| SCHEMBL3073489 | 0.90 | DRD3 (0.53) | DRD3HTR2ADRD2UTS2RPOLB | |
| SCHEMBL3080034 | 0.89 | HTR2A (0.56) | DRD3HTR2ADRD2POLB | |
| SCHEMBL3074537 | 0.89 | EPHX2 (0.56) | DRD3HTR2ADRD2 | |
| SCHEMBL3074535 | 0.89 | EPHX2 (0.56) | DRD3HTR2ADRD2 | |
| SCHEMBL27882701 | 0.88 | HRH1 (0.47) | DRD3HTR2A | |
| SCHEMBL14715678 | 0.87 | DRD3 (0.55) | DRD3HTR2ADRD2UTS2RPOLB | |
| SCHEMBL3087876 | 0.87 | DRD3 (0.55) | DRD3HTR2ADRD2UTS2RPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079693-B1 | ETHER DERIVATIVES DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS | HOFFMANN LA ROCHE (CH) | 2013-02-27 | — | — | EP | claimed |