Dimethylformamide

Dimethylformamide

SCHEMBL14715786

CN(C)C=O.OCCCO

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
ALDH1A1 P00352 2/20 0.35
USP2 O75604 1/20 0.35
ALOX15 P16050 1/20 0.35
MAPT P10636 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 2/20 0.32
HSD17B10 Q99714 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
AKR1B1 P15121 1/20 0.30
CAMK2A Q9UQM7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Butanediol SCHEMBL11494383 0.94 TSHR (0.56) TSHRALDH1A1USP2ALOX15MAPT
Dimethylformamide SCHEMBL29155529 0.91 TSHR (0.53) TSHRALDH1A1USP2ALOX15MAPT
Dimethylformamide SCHEMBL1835955 0.87
Dimethylformamide SCHEMBL28269265 0.87 TSHR (0.64) TSHRUSP2ALOX15MAPT
Butyl Alcohol SCHEMBL2408582 0.86 ALDH1A1 (0.58) TSHRALDH1A1SMN1; SMN2LMNAHSD17B10
1-Pentanol SCHEMBL28307899 0.84 SMN1; SMN2 (0.60) TSHRALDH1A1SMN1; SMN2LMNAHSD17B10
Hexane SCHEMBL3809026 0.82 ALDH1A1 (0.52) TSHRALDH1A1SMN1; SMN2LMNAHSD17B10
Octanol SCHEMBL27660517 0.82 TSHR (0.62) TSHRALDH1A1SMN1; SMN2LMNAHSD17B10
Dimethylformamide SCHEMBL8801229 0.81
Dimethylformamide SCHEMBL849515 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107033297-A Siliceous hyper branched polymer and the solidification compound containing the polymer 日产化学工业株式会社 2017-08-11 CN disclosed
CN-105263967-B Solidification compound comprising siloxane oligomer and inorganic particles 日产化学工业株式会社 2017-08-04 CN disclosed
CN-104507990-B9 Silicon-containing hyperbranched polymer and curable composition containing same 日产化学工业株式会社 2017-07-18 CN disclosed
CN-104755514-B Solidification compound comprising fluorine-containing hyper branched polymer and siloxane oligomer 日产化学工业株式会社 2017-04-05 CN disclosed
EP-1395833-B1 MISFOLDED PROTEIN SENSOR METHOD ADLYFE INC (US) 2013-02-27 EP disclosed