SCHEMBL1471627

SCHEMBL1471627

[CH]CF

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23044067 0.61
SCHEMBL381020 0.61
SCHEMBL2339 0.61
Ammonia Solution, Strong SCHEMBL25019 0.55
Hydrochloric Acid SCHEMBL9799153 0.55
SCHEMBL6113934 0.55
Water SCHEMBL25365379 0.55
SCHEMBL11038950 0.55
SCHEMBL26810 0.55
Hydrochloric Acid SCHEMBL9799147 0.55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 302 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11731946-B2 Broad spectrum antivirulence, anti-persistence compounds THE GENERAL HOSPITAL CORPORATION (US) 2023-08-22 US claimed
EP-2019679-B1 GLUCOSE TRANSPORT INHIBITORS AND METHODS OF USE THERACOS INC (US) 2018-06-20 EP claimed
US-7803778-B2 Glucose transport inhibitors and methods of use THERACOS, INC. (US) 2010-09-28 US claimed
EP-2019679-A2 GLUCOSE TRANSPORT INHIBITORS AND METHODS OF USE Theracos, Inc. (US) 2009-02-04 EP claimed
WO-2007140191-A2 GLUCOSE TRANSPORT INHIBITORS AND METHODS OF USE THERACOS, INC. (US) 2007-12-06 WO claimed
US-20070275907-A1 GLUCOSE TRANSPORT INHIBITORS AND METHODS OF USE SEED, BRIAN 2007-11-29 US claimed
US-20030125329-A1 Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity G.D. SEARLE & CO. 2003-07-03 US claimed
US-20030125328-A1 Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity G.D. SEARLE & CO. (US) 2003-07-03 US claimed
US-20030119833-A1 Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity G.D. SEARLE & CO. 2003-06-26 US claimed
US-20030114454-A1 Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity G.D. SEARLE & CO. (US) 2003-06-19 US claimed
US-20030087905-A1 Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity G.D. SEARLE & CO. 2003-05-08 US claimed
US-20030083331-A1 Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity G.D. SEARLE & CO. (US) 2003-05-01 US claimed
US-20030032644-A1 Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity G.D. SEARLE & CO. 2003-02-13 US claimed
US-20020165232-A1 Substituted N, N-disubstituted cycloalkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity SIKORSKI JAMES A (US) 2002-11-07 US claimed
US-20020165231-A1 Substituted N-heteroaryl-N-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity SIKORSKI JAMES A (US) 2002-11-07 US claimed
EP-1115693-A1 SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL $i(TERTIARY)-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY Monsanto Company (US) 2001-07-18 EP claimed
WO-2000018721-A1 SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL TERTIARY-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY MONSANTO COMPANY (US) 2000-04-06 WO claimed
EP-0543950-A4 FLUORINATED QUINOLINE POLYMERS AND THE CORRESPONDING FLUORINATED MONOMERS 1993-10-27 EP claimed
EP-0543950-A1 FLUORINATED QUINOLINE POLYMERS AND THE CORRESPONDING FLUORINATED MONOMERS HITACHI CHEMICAL CO., LTD. (JP) 1993-06-02 EP claimed
EP-0495585-A1 Antibacterial agents ELI LILLY AND COMPANY (US) 1992-07-22 EP claimed