SCHEMBL14716616

SCHEMBL14716616

O=C(O)c1ccc2cc(OC(=O)c3ccc(-c4ccc(O)cc4)cc3)ccc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.55
MEN1 O00255 3/20 0.55
MAPT P10636 2/20 0.55
TDP1 Q9NUW8 1/20 0.55
KDM4E B2RXH2 1/20 0.53
SENP1 Q9P0U3 1/20 0.47
PDGFRB P09619 1/20 0.47
PDGFRA P16234 1/20 0.47
ESR1 P03372 1/20 0.47
HGFAC Q04756 2/20 0.46
CASP3 P42574 1/20 0.46
SENP8 Q96LD8 1/20 0.46
SENP7 Q9BQF6 1/20 0.46
SENP6 Q9GZR1 1/20 0.46
TMPRSS2 O15393 1/20 0.46
MLNR O43193 1/20 0.46
ALDH1A1 P00352 1/20 0.46
F2 P00734 1/20 0.46
C1R P00736 1/20 0.46
F10 P00742 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9793342 0.95 KMT2A (0.60) KMT2AMEN1MAPTTDP1KDM4E
SCHEMBL5023133 0.94 KDM4E (0.50) KMT2AMEN1MAPTTDP1KDM4E
SCHEMBL5023168 0.94 KMT2A (0.53) KMT2AMEN1MAPTTDP1KDM4E
Paraben SCHEMBL4939242 0.94 HSD17B10 (0.53) KMT2AMEN1MAPTTDP1KDM4E
SCHEMBL6394400 0.93 HSD17B10 (0.51) KMT2AMEN1MAPTTDP1KDM4E
SCHEMBL2345023 0.93 HSD17B10 (0.51) KMT2AMEN1MAPTTDP1KDM4E
SCHEMBL8461211 0.91 KMT2A (0.55) KMT2AMEN1MAPTTDP1KDM4E
Paraben SCHEMBL5085969 0.91 HSD17B10 (0.53) KMT2AMEN1MAPTTDP1KDM4E
SCHEMBL5015779 0.91 HSD17B10 (0.53) KMT2AMEN1MAPTTDP1KDM4E
SCHEMBL7193077 0.90 HSD17B10 (0.49) KMT2AMEN1MAPTTDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130052336-A1 METHOD OF MANUFACTURING LAMINATED BASE MATERIAL AND METHOD OF MANUFACTURING LIQUID CRYSTAL POLYESTER FILM SUMITOMO CHEMICAL COMPANY, LIMITED 2013-02-28 US disclosed