SCHEMBL5023168

SCHEMBL5023168

O=C(O)c1ccc(OC(=O)c2ccc3cc(OC(=O)c4ccc(C(=O)O)cc4)ccc3c2)cc1.Oc1ccc(-c2ccc(O)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.53
MEN1 O00255 3/20 0.53
MAPT P10636 3/20 0.53
TDP1 Q9NUW8 2/20 0.53
HSD17B10 Q99714 1/20 0.50
ESR1 P03372 1/20 0.48
CASP3 P42574 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
KDM4E B2RXH2 1/20 0.46
HGFAC Q04756 2/20 0.46
CA12 O43570 2/20 0.46
CA9 Q16790 2/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA3 P07451 1/20 0.46
TYR P14679 1/20 0.46
DRD1 P21728 1/20 0.46
CA4 P22748 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5023133 0.97 KDM4E (0.50) KMT2AMEN1MAPTTDP1HSD17B10
SCHEMBL2345023 0.96 HSD17B10 (0.51) KMT2AMEN1MAPTTDP1HSD17B10
SCHEMBL6394400 0.96 HSD17B10 (0.51) KMT2AMEN1MAPTTDP1HSD17B10
SCHEMBL4124502 0.96 KMT2A (0.57) KMT2AMEN1MAPTTDP1HSD17B10
SCHEMBL5082470 0.94 HSD17B10 (0.50) KMT2AMEN1MAPTTDP1HSD17B10
Paraben SCHEMBL5085969 0.94 HSD17B10 (0.53) KMT2AMEN1MAPTTDP1HSD17B10
SCHEMBL5015779 0.94 HSD17B10 (0.53) KMT2AMEN1MAPTTDP1HSD17B10
SCHEMBL14716616 0.94 KMT2A (0.55) KMT2AMEN1MAPTTDP1HSD17B10
Paraben SCHEMBL4939242 0.94 HSD17B10 (0.53) KMT2AMEN1MAPTTDP1HSD17B10
SCHEMBL4138214 0.94 KMT2A (0.54) KMT2AMEN1MAPTTDP1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7335318-B2 Method for manufacturing wholly aromatic liquid-crystalline polyester resin KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2008-02-26 US disclosed
US-20060084747-A1 Method for manufacturing wholly aromatic liquid-crystalline polyester resin KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO 2006-04-20 US disclosed