⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3813934 | 0.97 | — | — | |
| SCHEMBL55912 | 0.82 | — | — | |
| SCHEMBL1916925 | 0.81 | — | — | |
| SCHEMBL22090630 | 0.79 | ODC1 (0.41) | — | |
| SCHEMBL23765660 | 0.78 | MEN1 (0.38) | — | |
| SCHEMBL19107454 | 0.78 | MEN1 (0.38) | — | |
| SCHEMBL454356 | 0.78 | MEN1 (0.38) | — | |
| SCHEMBL2639323 | 0.78 | MEN1 (0.38) | — | |
| SCHEMBL12775011 | 0.78 | MEN1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL4063567 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024012472-A1 | GLP-1/GIP DUAL AGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 杭州中美华东制药有限公司 | 2024-01-18 | — | — | WO | claimed |
| CN-117320740-A | GIP/GLP1 dual agonist treatment methods | 伊莱利利公司 | 2023-12-29 | — | — | CN | claimed |
| EP-4263518-A1 | NEW QUINAZOLINONE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-10-25 | — | — | EP | claimed |
| US-20230331682-A1 | NEW QUINAZOLINONE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2023-10-19 | — | — | US | claimed |
| CN-116768806-A | Substituted 1,2, 3-triazole compound, preparation method thereof and application thereof in preventing and treating plant diseases | 中国农业大学 | 2023-09-19 | — | — | CN | claimed |
| CN-116601147-A | Novel quinazolinone derivatives | 豪夫迈·罗氏有限公司 | 2023-08-15 | — | — | CN | claimed |
| WO-2022129259-A1 | NEW QUINAZOLINONE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2022-06-23 | — | — | WO | claimed |
| US-11261237-B2 | Modified pigment epithelium-derived factor (PEDF) peptides and uses thereof for treating neovascular diseases, inflammatory diseases, cancer, and for cytoprotection | NORTHWESTERN UNIVERSITY (US) | 2022-03-01 | — | — | US | claimed |
| US-11207423-B2 | Nanocarriers having surface conjugated peptides and uses thereof for sustained local release of drugs | NORTHWESTERN UNIVERSITY (US) | 2021-12-28 | — | — | US | claimed |
| US-10968198-B2 | Biaryltriazole inhibitors of macrophage migration inhibitory factor | YALE UNIVERSITY (US) | 2021-04-06 | — | — | US | claimed |
| EP-1648933-A1 | LONG LASTING INSULIN DERIVATIVES AND METHODS THEREOF | ConjuChem, Inc. (CA) | 2006-04-26 | — | — | EP | claimed |
| US-20050176643-A1 | Anti-obesity agents | CONJUCHEM, INC. (CA) | 2005-08-11 | — | — | US | claimed |
| JP-2005509624-A | — | — | 2005-04-14 | — | — | JP | claimed |
| WO-2005012346-A1 | LONG LASTING INSULIN DERIVATIVES AND METHODS THEREOF | CONJUCHEM, INC. (CA) | 2005-02-10 | — | — | WO | claimed |
| EP-1438053-A1 | PYRIMIDINE DERIVATIVES, PHARMACEUTICAL AGENT CONTAINING SAID COMPOUNDS, USE AND METHOD FOR MAKING SAME | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2004-07-21 | — | — | EP | claimed |
| US-20030171359-A1 | Suitable for treatment of illnesses characterised by excessive or abnormal cell proliferation; viral, bacterial, fungal and/or parasitic infections, skin diseases, bone diseases, cardiovascular diseases | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-09-11 | — | — | US | claimed |
| US-20030134989-A1 | Methods of synthesizing and using derivatives of [2-(2-aminoethoxy)ethoxy] acetic acid | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-07-17 | — | — | US | claimed |
| WO-2003032997-A1 | PYRIMIDINE DERIVATIVES, PHARMACEUTICAL AGENT CONTAINING SAID COMPOUNDS, USE AND METHOD FOR MAKING SAME | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-04-24 | — | — | WO | claimed |
| WO-2002042259-A2 | METHODS OF SYNTHESIZING AND USING DERIVATIVES OF [2-(2-AMINOETHOXY)ETHOXY] ACETIC ACID | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2002-05-30 | — | — | WO | claimed |
| WO-1995032736-A1 | IMMOBILIZATION OF BIOLOGICALLY ACTIVE MATERIALS AND DIAGNOSTIC AGENTS IN CROSS-LINKED POLY(ORGANOPHOSPHAZENES) | THE PENN STATE RESEARCH FOUNDATION (US) | 1995-12-07 | — | — | WO | claimed |