SCHEMBL14716865

SCHEMBL14716865

CC(=O)OC(F)C(F)C(F)F

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.43
TDP1 Q9NUW8 1/20 0.35
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM1 P11229 1/20 0.33
TBXA2R P21731 1/20 0.33
GALR3 O60755 1/20 0.32
MAPT P10636 1/20 0.32
BLM P54132 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 2/20 0.32
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL452396 0.83
SCHEMBL2112087 0.78 TSHR (0.34) TSHR
SCHEMBL28956532 0.78
SCHEMBL28623412 0.77 TSHR (0.48) TSHRTDP1CHRM2CHRM4CHRM1
SCHEMBL145572 0.77 ALDH1A1 (0.41) TSHRALDH1A1
SCHEMBL21681588 0.76
SCHEMBL29109567 0.75 TSHR (0.40) TSHRTDP1CHRM2CHRM4CHRM1
SCHEMBL1063328 0.74
SCHEMBL28354535 0.74
SCHEMBL27977192 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9427777-B2 Process for producing charge retention medium ASAHI GLASS COMPANY, LIMITED (JP) 2016-08-30 US disclosed
US-20130261248-A1 CHARGE RETENTION MEDIUM ASAHI GLASS COMPANY, LIMITED (JP) 2013-10-03 US disclosed
US-20130202810-A1 PROCESS FOR PRODUCING CHARGE RETENTION MEDIUM ASAHI GLASS COMPANY, LIMITED (JP) 2013-08-08 US disclosed
US-20130053493-A1 METHOD FOR PRODUCING FLUORINATED COPOLYMER COMPOSITION, COATING COMPOSITION, ARTICLE HAVING COATING FILM, AND MOLDED PRODUCT ASAHI GLASS COMPANY, LIMITED (JP) 2013-02-28 US disclosed