Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.42 |
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2927175 | 0.98 | CPB2 (0.43) | CPB2CPB1GPR84FFAR1CNR2 | |
| SCHEMBL10367905 | 0.90 | CNR2 (0.38) | GPR84FFAR1CNR2MAPTLCK | |
| SCHEMBL7260977 | 0.82 | AKR1C3 (0.37) | MAPTLMNA | |
| SCHEMBL10513500 | 0.80 | CPB2 (0.36) | CPB2CPB1MAPTALDH1A1 | |
| SCHEMBL4722745 | 0.80 | CSNK1E (0.36) | GPR84CNR2ALDH1A1 | |
| SCHEMBL5694337 | 0.78 | CSNK1E (0.38) | GPR84FFAR1CNR2ALDH1A1 | |
| SCHEMBL3639685 | 0.77 | CSNK1E (0.31) | — | |
| SCHEMBL21101056 | 0.76 | NR1I2 (0.38) | GPR84ALDH1A1LMNA | |
| SCHEMBL22819103 | 0.76 | NR1I2 (0.38) | GPR84ALDH1A1LMNA | |
| SCHEMBL3637539 | 0.76 | EP300 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915302-B2 | Crystal forms of pyrrolylheptanoic acid derivatives | DONG-A PHARM. CO., LTD. (KR) | 2011-03-29 | — | — | US | disclosed |
| CN-101657419-A | Novel crystal form of pyrrolylheptanoic acid derivative | DONG A PHARM CO LTD KR | 2010-02-24 | — | — | CN | disclosed |
| WO-2009084827-A3 | SYNTHETIC INTERMEDIATES, PROCESS FOR PREPARING PYRROLYLHEPTANOIC ACID DERIVATIVES THEREFROM | DONG-A PHARM.CO., LTD. (KR) | 2009-08-27 | — | — | WO | disclosed |
| WO-2009084827-A2 | SYNTHETIC INTERMEDIATES, PROCESS FOR PREPARING PYRROLYLHEPTANOIC ACID DERIVATIVES THEREFROM | DONG-A PHARM.CO., LTD. (KR) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009084827-A2 | SYNTHETIC INTERMEDIATES, PROCESS FOR PREPARING PYRROLYLHEPTANOIC ACID DERIVATIVES THEREFROM | DONG-A PHARM.CO., LTD. (KR) | 2009-07-09 | — | — | WO | disclosed |