Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 20/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3664219 | 0.92 | GRM5 (0.41) | GRM5 | |
| SCHEMBL3627855 | 0.89 | GRM5 (0.43) | GRM5 | |
| SCHEMBL2816086 | 0.85 | GRM5 (0.54) | GRM5 | |
| SCHEMBL2813710 | 0.85 | GRM5 (0.54) | GRM5 | |
| SCHEMBL3626221 | 0.84 | GRM5 (0.48) | GRM5 | |
| SCHEMBL990930 | 0.81 | GRM5 (0.47) | GRM5 | |
| SCHEMBL991428 | 0.81 | GRM5 (0.47) | GRM5 | |
| SCHEMBL1907392 | 0.81 | GRM5 (0.47) | GRM5 | |
| SCHEMBL3717173 | 0.81 | GRM5 (0.47) | GRM5 | |
| SCHEMBL4507971 | 0.77 | GRM5 (0.44) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130052644-A1 | Predictive Markers Useful in the Treatment of Fragile X Syndrome (FXS) | NOVARTIS AG (CH) | 2013-02-28 | — | — | US | disclosed |